144 Results for "

Galactosidase

" in MedChemExpress (MCE) Product Catalog:
Products (144)

144 Results for "Galactosidase" in MCE Product Catalog:

12
12 Publications Verification
Cat. No.: HY-K1089

MCE Cell Senescence β-Galactosidase Staining Kit can be used to evaluate the senescence of cells or tissues.

loading...
    loading...
11
11 Cited Publications
Cat. No.: HY-126839
CAS No.: 138777-25-0
Purity:  99.82%
Synonyms: 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside
C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) is a lipophilic green fluorescent substrate for β-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(β-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm) .
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-101895
CAS No.: 17817-20-8
Purity:  99.81%
Synonyms: FDG
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidaseex=485 nm, λem=535 nm).
loading...
    loading...
7
7 Cited Publications
Cat. No.: HY-15926
CAS No.: 369-07-3
Synonyms: 2-Nitrophenyl β-D-galactopyranoside
ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity.
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-15934
CAS No.: 7240-90-6
Synonyms: BCIG
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N8211
CAS No.: 94987-09-4
Gypenoside L is a saponin that can be found in Gynostemma pentaphyllum. Gypenoside L increases the SA-β-galactosidase activity, promotes the production of senescence-associated secretory cytokines. Gypenoside L also can activate p38 and ERK MAPK pathways and NF-κB pathway to induce senescence. Gypenoside L exhibits anti-tumor and anti-inflammatory activities .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-138936
CAS No.: 2629250-69-5
Purity:  99.75%
Target:  

p38 MAPK Apoptosis

Research Areas:  

Inflammation/Immunology

SSK1, a senescence-specific killing compound, is a β-galactosidase-targeted proagent attenuates inflammation. SSK1 is activated by lysosomal β-galactosidase and selectively killed senescent cells through the activation of p38 MAPK and induction of apoptosis .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-137862
CAS No.: 65528-98-5
Purity:  99.90%
Synonyms: 1-Oleoyl-sn-glycero-3-phosphate; 1-Oleoyl-LPA
Target:  

LPL Receptor

Research Areas:  

Neurological Disease

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) is an abundant lysophosphatidic acid (LPA) species with high biological activity due to its strong affinity for the LPA receptors. 1-Oleoyl lysophosphatidic acid is commonly used in most laboratories as a reagent for LPA receptor activation . 1-Oleoyl lysophosphatidic acid increases SRE-driven β-galactosidase activity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-14929A
CAS No.: 75172-81-5
Purity:  99.70%
Synonyms: GR181413A
Target:  

Glycosidase

Research Areas:  

Others

Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-D1224
CAS No.: 99792-79-7
Synonyms: CPRG
Chlorophenol red-β-D-galactopyranoside (CPRG) is an efficient and sensitive chromogenic substrate for β-galactosidase (HY-P2869), widely used in colorimetric assays. Chlorophenol red-β-D-galactopyranoside itself appears pale yellow. When it is specifically hydrolyzed by β-galactosidase, it releases chlorophenol red. The released chlorophenol red turns purple-red under alkaline or neutral pH conditions. This color change from yellow to red can be quantitatively detected at wavelengths of 540-572 nm using visible spectrophotometry .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P70303
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GLB1; Beta-Galactosidase; Prev. ELNR1; Elastin Receptor 1 (67kD); EBP; Galactosidase, Beta 1; Elastin Receptor 1, 67kDa; Elastin Receptor 1; Elastin Binding Protein; MPS4B; Acid Beta-Galactosidase; Galactosidase Beta 1; Lactase
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P7745
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSA; PPCA; Prev. PPGB; Protective Protein For Beta-Galactosidase; Prev. GSL; Beta-Galactosidase Protective Protein; Lysosomal Protective Protein; Alternative Protein CTSA; Carboxypeptidase C; Beta-Galactosidase 2; Carboxypeptidase Y-Like Kininase; Carbox
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-137845
CAS No.: 6160-78-7
Purity:  99.06%
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-114879
CAS No.: 118290-05-4
Purity:  98.43%
DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P2876
CAS No.: 9024-00-4
Target:  

Bacterial

Research Areas:  

Others

Tryptophanase is a zymogen-converting enzyme and inducible enzyme that can convert its inactive precursor form into an active enzyme without additional polypeptide synthesis. In Escherichia coli K12, tryptophanase functions as an inducible enzyme, and its induction kinetics are similar to those of β-galactosidase. Tryptophanase catalyzes the conversion of L-tryptophan to indole .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-D1633A
CAS No.: 206443-06-3
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
loading...
    loading...
Cat. No.: HY-P2869
CAS No.: 9031-11-2
Synonyms: EC 3.2.1.23; GAL
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

β-Galactosidase, E. coli (EC 3.2.1.23; GAL) is a glycoside hydrolase that hydrolyzes the β-glycosidic bonds formed between galactose and its organic moieties. β-Galactosidase, E. coli can hydrolyze lactose to form glucose and galactose, and enter glycolysis; it can also catalyze the transgalactosylation of lactose into allolactose; allolactose can be cracked into monosaccharides .
loading...
    loading...
Cat. No.: HY-E70285
Synonyms: B4GALT1 (Y285L)
Target:  

Glycosyltransferase

Research Areas:  

Metabolic Disease

beta-1,4-Galactosyltransferase 1 (Y285L) can enzymatic synthesis of the LacdiNAc motif. beta-1,4-Galactosyltransferase 1 (Y285L) can transfer of GalNAc from UDP-GalNAc .
loading...
    loading...
Cat. No.: HY-DY2002
CAS No.: 7240-90-6
X-GAL (BCIG) (solution) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
Solvent and Concentration: DMF: 20 mg/mL
loading...
    loading...
Cat. No.: HY-P2869C
CAS No.: 9031-11-2
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

β1-3,4 Galactosidase is a highly specific exoglycosidase that catalyzes the hydrolysis of terminal β1-3 and β1-4 linked galactose residues from oligosaccharides .
loading...
    loading...