26 Results for "

H37Ra

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "H37Ra" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N1976
CAS No.: 225110-25-8
Synonyms: (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol
(+)-(3R,8S)-Falcarindiol ((3R,8S)-Falcarindiol; 3 (R),8 (S),9 (Z)-Falcarindiol) is an orally active polyacetylene anti-mycobacterial agent. (+)-(3R,8S)-Falcarindiol exhibits antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and mycobacteria. Co-administration of (+)-(3R,8S)-Falcarindiol with (3R)-falcarinol alters the composition of gut microbiota, reduces colonic tumor lesions and slows down polyp growth. (+)-(3R,8S)-Falcarindiol can be used in research related to tuberculosis and colorectal cancer .
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1
1 Cited Publications
Cat. No.: HY-76293
CAS No.: 331963-29-2
Target:  

Bacterial

Research Areas:  

Infection

I2906 is an orally active isocitrate lyase (ICL) inhibitor with a Mycobacterium tuberculosis IC50 of 134.3 μg/mL. I2906 inhibits the growth of Mycobacterium tuberculosis. I2906 can be used for the research of tuberculosis .
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Cat. No.: HY-N3612
CAS No.: 2761-77-5
Synonyms: (+)-Communic acid
Target:  

Bacterial Akt MMP

Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging .
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Cat. No.: HY-N2876
CAS No.: 83529-71-9
Anisofolin A is a flavonoid that can be isolated from Anisomeles indica. Anisofolin A has antimalarial activity (IC50: 4.39 μM), and antimycobacterium activity (IC50: 4.50 μM) against M. tuberculosis H37Ra .
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Cat. No.: HY-126640
CAS No.: 359844-69-2
Target:  

Parasite

Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC50 is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC50 is 0.99, 0.51 and 1.4 µg/mL, respectively .
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Cat. No.: HY-149064
CAS No.: 2998587-72-5
Target:  

Bacterial

Research Areas:  

Infection

Antituberculosis agent-9 (Compound 5a) is an orally active antitubercular agent with an MIC of 0.5 μg/mL against H37Ra .
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Cat. No.: HY-173071
Target:  

Bacterial

Research Areas:  

Infection

DprE1-IN-13 (Compound 42) is the inhibitor for decaprenyl-phosphoryl-β-d-ribose oxidase (DprE1) with IC50 of 12.72 μM. DprE1-IN-13 inhibits Mycobacterium tuberculosis H37Ra with MIC50 of 1.071 μM .
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Cat. No.: HY-146104
CAS No.: 2409926-02-7
Target:  

Bacterial

Research Areas:  

Infection

Antimycobacterial agent-1 (compound 33) has selectively antimycobacterial activity against Mycobacterium tuberculosis (M. tuberculosis) H37Ra with a MIC value of 1 μg/ml. Antimycobacterial agent-1 has relatively low cytotoxicity in normal cells (Vero cells IC50 = 143.2 μg/ml) .
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Cat. No.: HY-152035
CAS No.: 3033421-29-0
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Mycobacterial Zmp1-IN-1 is a mycobacterial zinc metalloprotease-1 (Zmp1) inhibitor. Mycobacterial Zmp1-IN-1 has anti-mycobacterial activity for Mtb H37Ra in dose-dependent inhibition. Mycobacterial Zmp1-IN-1 can be used for the research of tuberculosis (TB) .
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Cat. No.: HY-135453
CAS No.: 206660-42-6
(-)-Pinocembrin exhibits anti-mycobacterium activity against mycobacteriuum tuberculosis H37Ra with an IC50 value of 1.11 mg/mL in dormant phase and 1.21 mg/mL in active phase, respectively. (-)-Pinocembrin has potent antiproliferative activity with IC50 values of 1.88-11.00 mg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines .
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Cat. No.: HY-139654
CAS No.: 2696301-42-3
Target:  

Bacterial

Research Areas:  

Infection

α/β-Hydrolase-IN-1 exhibits the best-in-class MICs of 50 μM (25 μg/mL) and 16 μM (8.4 μg/mL) against M. smegmatis and M. tuberculosis H37Ra, respectively.
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Cat. No.: HY-149581
CAS No.: 2906099-98-5
Target:  

Bacterial

Research Areas:  

Infection

DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates .
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Cat. No.: HY-N11646
CAS No.: 1421611-59-7
Target:  

Bacterial

Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .
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Cat. No.: HY-172397
Target:  

Bacterial

Research Areas:  

Infection

Mycobacterium Tuberculosis-IN-7 (Compound 4c) inhibits M. tuberculosis H37Ra with MIC of 5.34 μg/mL. Mycobacterium Tuberculosis-IN-7 exhibits slight cytotoxicity in cancer cell Vero, A549, and HepG2 (IC50s >50 μM) .
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Cat. No.: HY-143290
Target:  

Bacterial

Research Areas:  

Infection

Antibacterial agent 118 (compound 20) is an antimycobacterial agent. Antibacterial agent 118 shows antibacterial activity against Mtb H37Ra, M. aurum, M. smegmatis, Mtb H37Rv and M. avium with MIC values of 40.7, 10.2, 163.0, 62.5 and 62.5 μM, respectively. Antibacterial agent 118 can be used for the research of tuberculosis .
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Cat. No.: HY-178105
Target:  

Bacterial

Research Areas:  

Infection

LQFM326 is an antimycobacterial agent. LQFM326 shows MIC of 15.6 μg/mL against Mycobacterium tuberculosis H37Ra and 12.5 μg/mL against clinical strains. LQFM326 can cause depressions and pores to appear on the surface of the mycobacterium causing abscesses, shortening the bacterial length, increasing its thickness, and damaging the integrity of the cell wall. LQFM326 can be used for the research of tuberculosis .
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Cat. No.: HY-N11650
CAS No.: 1846584-06-2
Target:  

Bacterial

(22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid (compound 15) is an antitubercular agent with MIC value of 12.5 μg/mL for Mycobacterium tuberculosis H37Ra. (22S,24E)-3β,22-Diacetoxylanosta-7,9(11),24-trien-26-oic acid shows cytotoxicity with IC50 value of 32 μM for Vero cells .
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Cat. No.: HY-184685
Research Areas:  

Infection

Antimycobacterial agent-18 is a mycobacterial Fatty Acid Synthase I (FAS I) system inhibitor. Antimycobacterial agent-18 shows antimycobacterial activity against Mycobacterium tuberculosis H37Ra and drug-resistant Mycobacterium tuberculosis isolates, and partial activity against Mycobacterium abscessus. Antimycobacterial agent-18 can be used for the research of tuberculosis .
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Cat. No.: HY-179532
Target:  

Bacterial

Research Areas:  

Inflammation/Immunology

Antimycobacterial agent-14 (compound 20s) is an antimycobacterial agent with potent activity against Mycobacterium tuberculosis (M.tb) H37Ra strain with a MIC of 11.37 μM. Antimycobacterial agent-14 can be used for tuberculosis (TB) research .
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Cat. No.: HY-W748468
CAS No.: 24099-29-4
6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC50 of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC50 of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM .
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