2906099-98-5
2906099-98-5
Chemical Structure
DprE1-IN-9
- CAS No.: 2906099-98-5
- Formula:C22H25F3N4O2
- Molecular Weight:434.45
InChIKey: HUQTWGBRMNYWHL-UHFFFAOYSA-N
SMILES: O=C(C1=C2OCCN(CC3=NC(C)=C(C)N=C3C)C2=CC(C4CC4)=C1)NCC(F)(F)F
Biological Activity: DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates[1].
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DprE1-IN-9 | DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates. | |||||||||||||||||||||
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