2761-77-5
Chemical Structure
Communic acid
Synonym(s): (+)-Communic acid
- CAS No.: 2761-77-5
- Formula:C20H30O2
- Molecular Weight:302.45
IUPAC Name: (1S,4aR,5S,8aR)-1,4a-dimethyl-6-methylene-5-((E)-3-methylpenta-2,4-dien-1-yl)decahydronaphthalene-1-carboxylic acid
InChIKey: YGBZFOQXPOGACY-VWVSFFKRSA-N
SMILES: C[C@@]1([C@H]2C/C=C(C)/C=C)[C@](CCC2=C)([H])[C@](C)(CCC1)C(O)=O
Biological Activity: Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging[1][2][3].
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Communic acid | Communic acid ((+)-Communic acid) is a natural compound isolated from the branches of Platycladus orientalis. Communic acid displays minimum inhibitory concentration of 31 μM and IC50 of 15 μM against M. tuberculosis H37Ra.Communic acid exhibits protective effects against UVB-induced skin aging. | |||||||||||||||||||||
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- [1]. Samoylenko V, et al. Antiparasitic, nematicidal and antifouling constituents from Juniperus berries. Phytother Res. 2008;22(12):1570-1576. [Content Brief]
- [2]. Carpenter CD, et al. Anti-mycobacterial natural products from the Canadian medicinal plant Juniperus communis. J Ethnopharmacol. 2012;143(2):695-700. [Content Brief]
- [3]. Huh WB, et al. Brown Pine Leaf Extract and Its Active Component Trans-Communic Acid Inhibit UVB-Induced MMP-1 Expression by Targeting PI3K. PLoS One. 2015;10(6):e0128365. Published 2015 Jun 11. [Content Brief]
Keywords