2 Results for "

Heracleum maximum roots

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Heracleum maximum roots" in MCE Product Catalog:

1
(+)-(3R,8S)-Falcarindiol
(+)-(3R,8S)-Falcarindiol
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1 Cited Publications
Cat. No.: HY-N1976
CAS No.: 225110-25-8
Synonyms: (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol
Category:  

Infection Natural Products Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Plants Umbelliferae Disease Research Fields Inflammation/Immunology

(+)-(3R,8S)-Falcarindiol ((3R,8S)-Falcarindiol; 3 (R),8 (S),9 (Z)-Falcarindiol) is an orally active polyacetylene anti-mycobacterial agent. (+)-(3R,8S)-Falcarindiol exhibits antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and mycobacteria. Co-administration of (+)-(3R,8S)-Falcarindiol with (3R)-falcarinol alters the composition of gut microbiota, reduces colonic tumor lesions and slows down polyp growth. (+)-(3R,8S)-Falcarindiol can be used in research related to tuberculosis and colorectal cancer .
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6-Isopentenyloxyisobergapten
6-Isopentenyloxyisobergapten
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Cat. No.: HY-W748468
CAS No.: 24099-29-4
Category:  

Semenovia transiliensis Regel & Herder Apiaceae Coumarins Phenylpropanoids Plants

Target:  

Drug Derivative Bacterial

6-Isopentenyloxyisobergapten is a furanocoumarin found in the aerial parts of Semenovia transiliensis and the roots of Heracleum maximum. 6-Isopentenyloxyisobergapten has both selective phytotoxicity and antimycobacterial activity. 6-Isopentenyloxyisobergapten shows a minimum inhibitory concentration (MIC) of 166.5 μM and an IC50 of 27.4 μM against Mycobacterium tuberculosis H37Ra. 6-Isopentenyloxyisobergapten has an IC50 of 29 μM for the growth inhibition of Lemna paucicostata. 6-Isopentenyloxyisobergapten exhibits higher activity against Agrostis stolonifera than Lactuca sativa at a concentration of 1000 μM .
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