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- Decachaeta ovatifolia (DC.) R.M.King & H.Rob.
Decachaeta ovatifolia (DC.) R.M.King & H.Rob.
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Decachaeta ovatifolia (DC.) R.M.King & H.Rob. (8)
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- Formula: C17H24O2
- Molecular Weight: 260.37
(+)-(3R,8S)-Falcarindiol ((3R,8S)-Falcarindiol; 3 (R),8 (S),9 (Z)-Falcarindiol) is an orally active polyacetylene anti-mycobacterial agent. (+)-(3R,8S)-Falcarindiol exhibits antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and mycobacteria. Co-administration of (+)-(3R,8S)-Falcarindiol with (3R)-falcarinol alters the composition of gut microbiota, reduces colonic tumor lesions and slows down polyp growth. (+)-(3R,8S)-Falcarindiol can be used in research related to tuberculosis and colorectal cancer.
August 31
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- Formula: C11H12O4
- Molecular Weight: 208.21
6-Methoxymellein, a phytoalexin, is a NF-κB inhibitor. 6-Methoxymellein reduces nuclear localization and DNA binding activity of NF-κB p65 and p50 subunits. 6-Methoxymellein decreases mRNA transcription and secretion of IL-6 and IL-8. 6-Methoxymellein reduces the proportion of CD44+/CD24− breast cancer cells, decreases expression of c-Myc, Sox-2 and Oct4, inhibits proliferation and migration of breast cancer cells, and reduces mammosphere growth. 6-Methoxymellein inhibits fungal growth of Trichophyton rubrum and Botrytis cinerea, and inhibits Trichophyton rubrum biofilm formation via hyphal disintegration. 6-Methoxymellein can be used for the research of breast cancer, tinea corporis, and carrot post-harvest storage rot.
August 31
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- Formula: C15H12O6
- Molecular Weight: 288.25
Eriodictyol chalcone is an antioxidant that inhibits multiple key enzymes including 5-LOX (IC50=0.043 μM), aromatase/CYP19A1 (IC50=2.8 μM), PTPase 1B (IC50=1.26 μM), and COX (IC50=34 μM). Eriodictyol chalcone exhibits excellent free radical scavenging activity. Eriodictyol chalcone not only inhibits the growth of plasmodia and enhances the efficacy of Artemisinin (HY-B0094), but also reduces depression-like behaviors in animal models. Eriodictyol chalcone serves as a biosynthetic precursor for Aureusidin (HY-N9834). Eriodictyol chalcone is a potential dietary supplement and herbicide, and it can be applied to research on malaria, depression, breast cancer and other related diseases.
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- Formula: C22H22O12
- Molecular Weight: 478.40
6-Methoxykaempferol 3-glucoside (Kaempferol-6-methoxy-3-O-β-D-glucoside) is a natural product.
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- Formula: C17H26O3
- Molecular Weight: 278.39
Isofalcarintriol is a NRF2 activator and selective inhibitor of the mitochondrial ATP synthase. Isofalcarintriol can be used for aging study.
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- Formula: C19H20O5
- Molecular Weight: 328.36
12-epi-Teucvidin is a diterpenoid that can be obtained from Teucrium fourrifarium. 12-epi-Teucvidin has the potential for research of antioxidant, analgesic, and anti-inflammatory.
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