6 Results for "

Human skeletal myoblasts

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Human skeletal myoblasts" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99388
CAS No.: 1429201-24-0
Synonyms: REGN-1033; SAR391786

Target:  

TGF-beta/Smad

Research Areas:  

Inflammation/Immunology

Trevogrumab (REGN-1033) is a monoclonal antibody targeting GDF8 (growth differentiation factor 8, also known as myostatin). Trevogrumab is used in research on muscle wasting conditions, including disuse atrophy, chronic diseases, and changes in food and nutrient intake .
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Cat. No.: HY-Q40175
CAS No.: 438474-67-0
Target:  

Parasite

Research Areas:  

Infection

Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory activity against T. b. brucei, with an IC50 of 1.15 μM. Antitrypanosomal agent 9 can be used for human African trypanosomiasis (HAT) research .
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Cat. No.: HY-134310
CAS No.: 1353586-18-1
Target:  

Heme Oxygenase (HO)

Research Areas:  

Inflammation/Immunology

QC-308 hydrochloride is a HO-1/HO-2 inhibitor, with an IC50 of 0.27 μM against rat HO-1 and an IC50 of 0.46 μM against rat HO-2. QC-308 hydrochloride inhibits the activities of rat HO-1 and HO-2 in carbon monoxide generation assays using spleen and brain microsomes, respectively. QC-308 hydrochloride also exhibits senolytic activity, reducing the survival rate of adipogenic progenitor cells in skeletal muscle fibers of senescent mice and human skeletal muscle myoblasts. QC-308 hydrochloride is applicable for senescence-related research .
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Cat. No.: HY-182604
CAS No.: 1353712-58-9
Target:  

Heme Oxygenase (HO)

Research Areas:  

Inflammation/Immunology

QC-308 is a HO-1/HO-2 inhibitor, with an IC50 of 0.27 μM against rat HO-1 and an IC50 of 0.46 μM against rat HO-2. QC-308 inhibits the activities of rat HO-1 and HO-2 in carbon monoxide generation assays using spleen and brain microsomes, respectively. QC-308 also exhibits senolytic activity, reducing the survival rate of adipogenic progenitor cells in skeletal muscle fibers of senescent mice and human skeletal muscle myoblasts. QC-308 is applicable for senescence-related research .
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Cat. No.: HY-N20724
CAS No.: 93124-90-4
Ageconyflavone C is a natural pentamethoxyflavonoid found in the aerial parts of Ageratum conyzoides L. Ageconyflavone C inhibits Trypanosoma brucei rhodesiense, Leishmania donovani, and Chloroquine (HY-17589A)- and Pyrimethamine (HY-18062)-resistant Plasmodium falciparum K1, with IC50 values of 7.8, 9.2, and 9.25 μM, respectively. Ageconyflavone C can be used in studies related to anti-protozoal and parasitic infection research .
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Cat. No.: HY-W054427
CAS No.: 70842-04-5
Target:  

Parasite

Research Areas:  

Infection Metabolic Disease

Ro 13-3978 is an orally active antischistosomal agent. Ro 13-3978 exhibits excellent in vivo antischistosomal activity against juvenile and adult Schistosoma mansoni infections. Ro 13-3978 shows no in vivo activity against E. caproni and F. hepatica. Ro 13-3978 blocks dihydrotestosterone-induced proliferation of androgen-dependent cells. Ro 13-3978 can be used in research related to schistosomiasis .
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