2. Metabolic Enzyme/Protease
  3. Heme Oxygenase (HO)
  4. QC-308

QC-308 is a HO-1/HO-2 inhibitor with an HO-1 IC50 of 0.27 μM and an HO-2 IC50 of 0.46 μM. QC-308 coordinates heme iron(II) to disrupt catalysis. QC-308 can be used for research of HO-1 inhibition mechanisms in cancer.

For research use only. We do not sell to patients.

QC-308

QC-308 Chemical Structure

CAS No. : 1353712-58-9

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QC-308 Related Antibodies

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Description

QC-308 is a HO-1/HO-2 inhibitor with an HO-1 IC50 of 0.27 μM and an HO-2 IC50 of 0.46 μM. QC-308 coordinates heme iron(II) to disrupt catalysis. QC-308 can be used for research of HO-1 inhibition mechanisms in cancer[1].

IC50 & Target[1]

HO-1

0.27 μM (IC50)

HO-2

0.46 μM (IC50)

In Vitro

QC-308 inhibits heme oxygenase-1 from rat spleen microsomal fractions with an IC50 of 0.27 μM and heme oxygenase-2 from rat brain microsomal fractions with an IC50 of 0.46 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

QC-308 Related Antibodies
Molecular Weight

290.36

Formula

C19H18N2O
CAS No.
SMILES

O=C(CC(C1=CC=CC=C1)C2=CC=CC=C2)CN3C=NC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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QC-308 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

QC-3081353712-58-9QC308QC 308Heme Oxygenase (HO)Heme Oxygenaserat brain microsomal fractionsrat spleen microsomal fractionsheme oxygenase-1HO-1HO-2heme iron(II)heme oxygenase-2Inhibitorinhibitorinhibit

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