QC-308
QC-308 is a HO-1/HO-2 inhibitor with an HO-1 IC50 of 0.27 μM and an HO-2 IC50 of 0.46 μM. QC-308 coordinates heme iron(II) to disrupt catalysis. QC-308 can be used for research of HO-1 inhibition mechanisms in cancer.
For research use only. We do not sell to patients.
- CAS No.: 1353712-58-9
- Formula: C19H18N2O
- Molecular Weight:290.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HO-1 0.27 μM (IC50) |
HO-2 0.46 μM (IC50) |
QC-308 inhibits heme oxygenase-1 from rat spleen microsomal fractions with an IC50 of 0.27 μM and heme oxygenase-2 from rat brain microsomal fractions with an IC50 of 0.46 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1353712-58-9
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Molecular Weight 290.36
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Formula C19H18N2O
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SMILES
O=C(CC(C1=CC=CC=C1)C2=CC=CC=C2)CN3C=NC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
QC-308 Related Classifications
HY-182604 Related Classifications
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