2 Results for "

Influenza virus-IN-8

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Influenza virus-IN-8" in MCE Product Catalog:

Cat. No.: HY-155476
CAS No.: 1627115-50-7
Target:  

Influenza Virus

Research Areas:  

Infection

Influenza virus-IN-8 (compound A4) is an inhibitor of influenza virus (Influenza Virus) that induces viral nucleoprotein (NP) aggregation and prevents its nuclear accumulation. Influenza virus-IN-8 has broad-spectrum anti-influenza activity and can inhibit the replication and transcription of influenza A virus. Influenza virus-IN-8 also inhibits Oseltamivir (HY-13317)-resistant H1N1/pdm09 strains .
loading...
    loading...
Cat. No.: HY-149034
Synonyms: S5
Target:  

Influenza Virus

Research Areas:  

Infection Cancer

Influenza A virus-IN-8 (S5) is a macrocyclic peptide with no cytotoxic. Influenza A virus-IN-8 is also a potent Influenza A Virus (IAV) inhibitor (with sufficient protease stability) with IC50s of 6.7 and 6.6 nM for H1 and H5 variants, respectively. Influenza A virus-IN-8 shows good affinitiescan to H1 variants, binds to a conserved region in the HA stem with a Kd of 1.0 nM .
loading...
    loading...