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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Isoquinoline derivatives
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Isoquinoline derivatives" in MCE Product Catalog:
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Research Areas:
Immunoproteasome inhibitor 1 is a potent, reversible, time-independent immunoproteasome and proteasome inhibitor (Kis of 1.18, 0.27, 1.91 μM in β5c, β1i, β5i submits, respectively). Immunoproteasome inhibitor 1 can be used for the research of certain neoplastic diseases .
Cat. No.: HY-W004698
CAS No.: 628692-15-9
Cat. No.: HY-172530
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Heptanoyl-coenzyme A (Heptanoyl-CoA) tetrasodium is a derivative of CoA. Heptanoyl-coenzyme A tetrasodium is an inhibitor of butyryl-CoA acetate-CoA transferase (BUT) and inhibits butyric acid synthesis. Heptanoyl-coenzyme A tetrasodium blocks the improvements in motor function induced by the isoquinoline alkaloid Berberine (HY-N0716) .
Cat. No.: HY-114814A
CAS No.: 610782-83-7
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(+)-ORM-10921 Free base is a compound that exhibits significant biological activity, particularly in the context of chemical synthesis studies and the preparation of pyrido [1,2-b] isoquinoline derivatives. (+)-ORM-10921 Free base is utilized as an active reagent in multi-component reactions involving alkynes and isoquinolinium ylides. (+)-ORM-10921 Free base plays a crucial role in the advancement of synthetic organic chemistry by enabling the formation of complex molecular structures.
Cat. No.: HY-162962
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IDO1/TDO-IN-7 (Compound 43b), an isoquinoline derivative, is a potent dual IDO1/TDO inhibitor, with IC50s of 0.31 μM and 0.08 μM, respectively. IDO1/TDO-IN-7 displays acceptable pharmacokinetic profiles and potent antitumor efficacy with low toxicity in B16-F10 tumor model .
Cat. No.: HY-168623
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EGFR-IN-134 (compound 3f), a triazolo[3,4-a]isoquinoline derivative, is a potent EGFR inhibitor with an IC50 of 0.023 µM. EGFR-IN-134 induces apoptosis and necrosis. EGFR-IN-134 initiates cell cycle arrest at the G2/M and pre-G1 phases, downregulates anti-apoptotic protein Bcl2 and upregulates pro-apoptotic proteins: p53, Bax, and caspases 3, 8, and 9. EGFR-IN-134 shows antiproliferative and anticancer activity .
Cat. No.: HY-118587
CAS No.: 55393-37-8
Synonyms: HE 165
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CH-102 (HE 165) is an isoquinoline derivative. CH-102 exhibits significant anti-platelet aggregation and antithrombotic activities. CH-102 can be used in the study of angina pectoris .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
