Pks13-IN-3
Pks13-IN-3 is a furo[2,3-b]isoquinoline derivative and Pks13 inhibitor with an IC50 of 1.12 μM. Pks13-IN-3 reduces inhibition of the hERG ion channel. Pks13-IN-3 can be used for the research of tuberculosis.
For research use only. We do not sell to patients.
- Formula: C23H17NO6
- Molecular Weight:403.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Pks13-IN-3 (B23) potently inhibits Pks13-TE with an IC50 of 1.12 μM[1].
Pks13-IN-3 has reduced hERG channel inhibition, with an IC50 greater than 10 μM in HEK293 cells[1].
Pks13-IN-3 has a favorable safety profile, with CC50 values greater than 100 μM in HepG2 and Vero cells, and greater than 50 μM in 293T cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 403.38
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Formula C23H17NO6
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SMILES
O=C1C2=C(OC3=C2C(CN1CC4=CC=CC(O)=C4O)=C(C=C3)O)C5=CC=C(C=C5)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pks13-IN-3 Related Classifications
HY-181745 Related Classifications
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