Pks13-IN-3
Pks13-IN-3 is a furo[2,3-b]isoquinoline derivative and Pks13 inhibitor with an IC50 of 1.12 μM. Pks13-IN-3 reduces inhibition of the hERG ion channel. Pks13-IN-3 can be used for the research of tuberculosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C23H17NO6
- 分子量:403.38
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Pks13-IN-3 (B23) potently inhibits Pks13-TE with an IC50 of 1.12 μM[1].
Pks13-IN-3 has reduced hERG channel inhibition, with an IC50 greater than 10 μM in HEK293 cells[1].
Pks13-IN-3 has a favorable safety profile, with CC50 values greater than 100 μM in HepG2 and Vero cells, and greater than 50 μM in 293T cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 403.38
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分子式 C23H17NO6
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SMILES
O=C1C2=C(OC3=C2C(CN1CC4=CC=CC(O)=C4O)=C(C=C3)O)C5=CC=C(C=C5)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)