2 Results for "

KRAS inhibitor37

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "KRAS inhibitor37" in MCE Product Catalog:

Cat. No.: HY-169311
CAS No.: 3058573-95-5
Target:  

Ras

Research Areas:  

Cancer

KRAS inhibitor-37 (compound 2) is a potent KRAS inhibitor with KDs of 0.004 nM, 0.041 nM, 0.019 nM and 0.144 nM for KRAS wild type, KRAS G12D, KRAS G12C and KRAS G12V by SPR binding assay, respectively. KRAS inhibitor-37 inhibits cell proliferation with IC50s of <2 nM-14 nM for H358, SW620, PANC08.13 cells, respectively. KRAS inhibitor-37 has the potential for cancer research .
loading...
    loading...
Cat. No.: HY-143590
CAS No.: 2241720-04-5
Target:  

Ras

Research Areas:  

Cancer

KRAS G12C inhibitor 37 is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12C inhibitor 37 has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2018143315A1, compound 65) .
loading...
    loading...