1 Result for "

KRAS-IN-48 free base

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KRAS-IN-48 free base" in MCE Product Catalog:

Cat. No.: HY-179300
CAS No.: 3074833-86-3
Target:  

Ras

Research Areas:  

Cancer

KRAS-IN-48 free base (Compound 1-01) is a mutant KRAS inhibitor, with Kd values of 2.58 nM and 5.49 μM for KRAS G12D and KRAS G12V, respectively. KRAS-IN-48 free base affects pERK expression in cells harboring KRAS G12D and KRAS G12V mutations, with IC50 values of 1.1 μM and 1.51 μM, respectively. KRAS-IN-48 free base can be used in the research of cancer .
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