2 Results for "

Kazinol B

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Kazinol B" in MCE Product Catalog:

Kazinol B
Kazinol B
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Cat. No.: HY-N3426
CAS No.: 99624-27-8
Category:  

other families Metabolic Disease Phenols Polyphenols Plants Disease Research Fields

Target:  

NO Synthase Akt AMPK

Kazinol B, a prenylated flavan with a dimethyl pyrane ring, is an inhibitor of nitric oxide (NO) production. Kazinol B improves insulin sensitivity by enhancing glucose uptake via the insulin-Akt signaling pathway and AMPK activation. Kazinol B has the potential for diabetes mellitus research .
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(2R)-Kazinol B
(2R)-Kazinol B
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Cat. No.: HY-N3426A
CAS No.: 2097138-89-9
Category:  

Thymelaeaceae Daphne giraldii Nitsche Coumarins Phenylpropanoids Plants

Target:  

Drug Isomer Apoptosis Autophagy AMPK

(2R)-Kazinol B is a prenylated flavane enantiomer found in the stem and root barks of Daphne giraldii, and it is also an isomer of Kazinol B (HY-N3426). (2R)-Kazinol B exerts selective cytotoxicity against liver cancer cells, induces apoptosis via both intrinsic and extrinsic pathways, and triggers protective autophagy through AMPK activation. (2R)-Kazinol B can be used in the research of liver cancer .
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