5 Results for "

Kuramochi

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Kuramochi" in MCE Product Catalog:

Cat. No.: HY-133618
CAS No.: 2414418-49-6
Purity:  99.84%
Target:  

Wee1 PROTACs Apoptosis

Research Areas:  

Cancer

Pomalidomide-C3-adavosertib is a rapid and selective PROTAC Wee1 degrader (IC50=3.58 nM). Pomalidomide-C3-adavosertib shows anti-cancer cell proliferation activity, and induces apoptosis .
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Cat. No.: HY-P99828
CAS No.: 1869928-62-0
Synonyms: PF-06523435; hu24

Target:  

ADC Antibodies RET PERK ROR

Research Areas:  

Cancer

Cofetuzumab (PF-06523435) is a humanized IgG1-κ monoclonal antibody targeting PTK7. The expression system of Cofetuzumab is typically CHO (Chinese hamster ovary) cells. Cofetuzumab downregulates PTK7 expression, modulates its downstream signaling pathways, and inhibits tumor sphere formation of ovarian cancer cells. Cofetuzumab can be used to synthesize the ADC molecule Cofetuzumab pelidotin (HY-P99829). Cofetuzumab is applicable to the research of tumors such as ovarian cancer .
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Cat. No.: HY-104000
CAS No.: 1445830-50-1
Purity:  99.74%
Target:  

Ser/Thr Protease

Research Areas:  

Cancer

BAY-320 is a selective and ATP-competitive Bub1 inhibitor that inhibits the kinase activity of Bub1 with an IC50 of 680 nM. BAY-320 inhibits endogenous Bub1-mediated Sgo1 localization. BAY-320 affects cellular mitotic chromosome arrangement and spindle assembly. BAY-320 inhibits cell proliferation. BAY-320 can be used in the study of cancer such as ovarian cancer and cervical cancer .
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Cat. No.: HY-156920
CAS No.: 158983-23-4
Target:  

Necroptosis RIP kinase

Research Areas:  

Inflammation/Immunology Cancer

VDX-111 is an analog of vitamin D. VDX-111 exhibits cytotoxicity in ovarian cancer cells through upregulation of RIPK1/RIPK3 pathway and induction of necroptosis. VDX-111 promotes expressions of cytokines and exhibits antitumor activity in mouse model .
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Cat. No.: HY-189497
CAS No.: 3133169-21-5
Target:  

CDK

Research Areas:  

Cancer

CCNE1 degrader-2 is an orally active CCNE1 degrader with a paDC50 of 7.7 nM. CCNE1 degrader-2 promotes the targeted degradation of Cyclin E1 protein. CCNE1 degrader-2 inhibits tumor cell proliferation and exerts antitumor activity in CDX in vivo models. CCNE1 degrader-2 is used in research on cancers such as ovarian cancer and breast cancer .
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