Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
63 Results for "
Lipopeptide
" in MedChemExpress (MCE) Product Catalog:
Products (63)
63 Results for "Lipopeptide" in MCE Product Catalog:
26
Category:
Infection Microorganisms Macrolide Antibiotics Antibiotics Mammalian Cell Culture Disease Research Antibacterial Disease Research Fields
Target:
8
7
7 Cited Publications
Target:
5
5 Cited Publications
1
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
1
1 Cited Publications
Cat. No.: HY-P3496
CAS No.: 1322711-38-5
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-163001
CAS No.: 2408008-21-7
Category:
Cat. No.: HY-P3884
CAS No.: 459844-20-3
Target:
Research Areas:
Cat. No.: HY-P2233
CAS No.: 67076-74-8
Target:
Research Areas:
Target:
Research Areas:
Cat. No.: HY-165613
CAS No.: 656831-18-4
Synonyms: Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine
Research Areas:
Pam2Cys (Dipalmitoyl-S-glyceryl-cysteine; S-[2,3-Bis(palmitoyloxy)propyl]cysteine) is a TLR2 agonist and immunostimulant. Pam2Cys binds to TLR2 to activate dendritic cells and trigger the TLR2-dependent NF-κB signaling pathway. Pam2Cys also induces dendritic cell maturation by upregulating the expression of cell surface MHC II molecules. Pam2Cys activates innate immune signaling pathways, drives pro-inflammatory and antimicrobial responses, enhances the expression of macrophage activation markers, increases phagocytic activity, induces the release of IL-12 and pro-inflammatory cytokines, and polarizes macrophages into a pro-inflammatory, antimicrobial phenotype without interfering with IL-10-induced macrophage polarization. Pam2Cys also serves as the lipid moiety in synthetic lipopeptide vaccines and possesses self-adjuvant properties. Pam2Cys enhances the immunogenicity of conjugated peptide segments and induces cellular and humoral immune responses. However, it does not activate CD4 T cells in mouse splenocyte cultures when used alone. Pam2Cys activates pulmonary TLR2 signaling pathways, triggers innate immune responses, recruits neutrophils and macrophages, induces the secretion of various cytokines, alleviates symptoms and damages associated with influenza A virus infection in mice without impairing adaptive immunity. Pam2Cys can be used in studies related to tuberculosis and influenza A virus infection .
Target:
Cat. No.: HY-125576
CAS No.: 26034-16-2
Cat. No.: HY-P0104
CAS No.: 1447824-23-8
Target:
Research Areas:
Synonyms: P1pal-7
Research Areas:
Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
Target:
Research Areas:
Cat. No.: HY-P10586A
Synonyms: MALP-2 TFA
Target:
Research Areas:
Cat. No.: HY-P11455A
Cat. No.: HY-A0248AS
Target:
Cat. No.: HY-P3511
CAS No.: 302327-42-0
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
