2 Results for "

MC-VA-PAB-Exatecan

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MC-VA-PAB-Exatecan" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-147270
CAS No.: 2680543-57-9
Purity:  99.58%
Research Areas:  

Cancer

MC-VA-PAB-Exatecan is a agent-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity .
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Cat. No.: HY-171747
AMT-562 is an antibody-drug conjugate (ADC) consisting of a novel anti-HER3 antibody Ab562 (HY-P991505) conjugated to the linker MC-VA-PAB and the topoisomerase I inhibitor Exatecan (HY-13631). The ADC toxic molecule and linker portion are MC-VA-PAB-Exatecan (HY-147270). AMT-562 can induce apoptosis and has antitumor activity against pancreatic, esophageal, and gastric cancers .
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