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Mcl-1-IN-22

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-183601
    Mcl-1-IN-22

    		Bcl-2 Family Apoptosis Cancer
    Mcl-1-IN-22 is a selective Mcl-1 inhibitor with a Ki of 0.015 μM. Mcl-1-IN-22 binds selectively to Mcl-1, disrupts the Mcl-1/Bak complex to release free Bak, triggering intrinsic apoptosis. Mcl-1-IN-22 can be used for the research of ovarian cancer .
    Mcl-1-IN-22
  • HY-183601A
    Mcl-1-IN-22 hydrochloride

    		Bcl-2 Family Apoptosis Cancer
    Mcl-1-IN-22 hydrochloride is a tetrahydro-β-carboline-based Mcl-1 inhibitor with a Ki of 0.015 μM. Mcl-1-IN-22 hydrochloride shows antitumor activity, induces apoptosis and produces synergistic antitumor effects in combination with Cisplatin (HY-17394) and Paclitaxel (HY-B0015). Mcl-1-IN-22 hydrochloride can be used for the research of cancer, such as ovarian cancer .
    Mcl-1-IN-22 hydrochloride
  • HY-170763B
    (-)-Mcl-1 inhibitor 22

    		Bcl-2 Family Apoptosis Cancer
    (-)-Mcl-1 inhibitor 22 (compound 38) is an Mcl-1 inhibitor that works by blocking the interaction between Mcl-1 and pro-apoptotic proteins, reducing the anti-apoptotic activity of Mcl-1. (-)-Mcl-1 inhibitor 22 can be used in cancer research .
    (-)-Mcl-1 inhibitor 22
  • HY-170763
    Mcl-1 inhibitor 22

    		Apoptosis Bcl-2 Family Cancer
    Mcl-1 inhibitor 22 (Example 36) is a myeloid cell leukemia-1 (MCL-1) inhibitor which inhibits the antiapoptotoic activity of MCL-1 by inhibiting its interaction with proapototic proteins. Mcl-1 inhibitor 22 exhibits anti-proliferation activities against various cancer cell lines and can be utilized in cancer research .
    Mcl-1 inhibitor 22
  • HY-170763A
    (+)-Mcl-1 inhibitor 22

    		Apoptosis Bcl-2 Family Cancer
    (+)-Mcl-1 inhibitor 22 (Example 37) is a myeloid cell leukemia-1 (MCL-1) inhibitor which inhibits the antiapoptotoic activity of MCL-1 by inhibiting its interaction with proapototic proteins. (+)-Mcl-1 inhibitor 22 exhibits anti-proliferation activities against various cancer cell lines and can be utilized in cancer research .
    (+)-Mcl-1 inhibitor 22

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