2332611-98-8
2332611-98-8
Chemical Structure
(+)-Mcl-1 inhibitor 22
- CAS No.: 2332611-98-8
- Formula:C33H33ClFN3O4
- Molecular Weight:590.08
InChIKey: DSRUJIWLAZNHGL-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(C2=C3N1CCCCOCC4=NN(C(CC)=C4C3=C(C=C2)Cl)C)CCCOC5=CC=CC6=C5C=CC(F)=C6
Biological Activity: (+)-Mcl-1 inhibitor 22 (Example 37) is a myeloid cell leukemia-1 (MCL-1) inhibitor which inhibits the antiapoptotoic activity of MCL-1 by inhibiting its interaction with proapototic proteins. (+)-Mcl-1 inhibitor 22 exhibits anti-proliferation activities against various cancer cell lines and can be utilized in cancer research[1].
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(+)-Mcl-1 inhibitor 22 | (+)-Mcl-1 inhibitor 22 (Example 37) is a myeloid cell leukemia-1 (MCL-1) inhibitor which inhibits the antiapoptotoic activity of MCL-1 by inhibiting its interaction with proapototic proteins. (+)-Mcl-1 inhibitor 22 exhibits anti-proliferation activities against various cancer cell lines and can be utilized in cancer research. | |||||||||||||||||||||
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