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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
Microtubule stabilizer
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "Microtubule stabilizer" in MCE Product Catalog:
10
Epothilone B is a microtubule stabilizer (MSA) with a Ki of 0.71μM, and is a MSA with blood-brain barrier permeability. Epothilone B acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation .
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4 Cited Publications
Synonyms: Epothilone D; UTD1; KOS 862
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Utidelone (Epothilone D) is a potent microtubule stabilizer.
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1 Cited Publications
Cat. No.: HY-N4208
CAS No.: 2230777-09-8
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Taccalonolide AJ is a microtubule stabilizer and antiproliferative agent with an IC50 of 4.2 nM against β-tubulin (β-tubulin) D226. Taccalonolide AJ increases cellular microtubule density, induces microtubule bundling, triggers G2/M cell cycle arrest with abnormal mitotic spindles, and inhibits cancer cell proliferation. Taccalonolide AJ can be used in the research of oral cancer, breast cancer, solid tumors, as well as tumors resistant to Paclitaxel (HY-B0015) and Doxorubicin (HY-15142A) .
Cat. No.: HY-N2416
CAS No.: 108885-68-3
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TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain .
Cat. No.: HY-176540
CAS No.: 2699937-76-1
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Microtubule stabilizer-1 (compound 69) is a brain-penetrant microtubule (MT) stabilizer. Microtubule stabilizer-1 increases acetylated α-tubulin (AcTub) levels and prevents the characteristic loss of neuronal MTs that is observed after incubation with Okadaic acid (HY-N6785). Microtubule stabilizer-1 can be used for the study of Alzheimer’s disease (AD) and related neurodegenerative tauopathies .
Cat. No.: HY-N3028
CAS No.: 108885-69-4
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Cat. No.: HY-15278A
Purity: 95.11%
Synonyms: (16R)-Epothilone D; (16R)-UTD1; (16R)-KOS 862
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(16R)-Utidelone ((16R)-Epothilone D) is the isomer of Utidelone (HY-15278), and can be used as an experimental control. Utidelone (KOS 862) is a potent microtubule stabilizer.
Cat. No.: HY-162161
CAS No.: 301844-13-3
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Flutax-2 is an active fluorescent derivative of Paclitaxel (HY-B0015) that binds to polymerized αβ-tubulin dimers. Flutax-2 is applicable for imaging microtubules in live cells, isolated cytoskeletons and parasites (Ex/Em=496/526 nm) .
Cat. No.: HY-N11067
CAS No.: 134954-57-7
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Cat. No.: HY-13656
CAS No.: 691868-19-6
Synonyms: KOS-1803
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Isofludelone (KOS-1803) is a potential microtubule stabilizer for the study of solid tumors. Isofludelone has antitumor activity .
Cat. No.: HY-15278R
CAS No.: 189453-10-9
Synonyms: Epothilone D (Standard); UTD1 (Standard); KOS 862 (Standard)
Utidelone (Standard) (Epothilone D (Standard)) is the analytical standard ofUtidelone. This product is intended for research and analytical applications. Utidelone is a potent microtubule stabilizer .
Cat. No.: HY-155647
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Microtubule stabilizing agent-1 (compound 3l) is a Paclitaxel derivative that efficiently promotes tubulin polymerization. Microtubule stabilizing agent-1 shows antitumor efficacy .
Cat. No.: HY-17029R
CAS No.: 152044-54-7
Synonyms: EPO 906 (Standard); Patupilone (Standard)
Epothilone B (Standard) is the analytical standard of Epothilone B. This product is intended for research and analytical applications. Epothilone B is a microtubule stabilizer with a Ki of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.
Cat. No.: HY-W754654
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
