2699937-76-1
2699937-76-1
Chemical Structure
Microtubule stabilizer-1
- CAS No.: 2699937-76-1
- Formula:C18H17ClF2N6
- Molecular Weight:390.82
InChIKey: NAOUKDPJPWIYSB-SECBINFHSA-N
SMILES: CC(C)(C)[C@@H](C)NC1=C(C2=C(C=C(C=C2F)C#N)F)C(Cl)=NC3=NC=NN31
Biological Activity: Microtubule stabilizer-1 (compound 69) is a brain-penetrant microtubule (MT) stabilizer. Microtubule stabilizer-1 increases acetylated α-tubulin (AcTub) levels and prevents the characteristic loss of neuronal MTs that is observed after incubation with Okadaic acid (HY-N6785). Microtubule stabilizer-1 can be used for the study of Alzheimer’s disease (AD) and related neurodegenerative tauopathies[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Microtubule stabilizer-1 | 99.47% | Microtubule stabilizer-1 (compound 69) is a brain-penetrant microtubule (MT) stabilizer. Microtubule stabilizer-1 increases acetylated α-tubulin (AcTub) levels and prevents the characteristic loss of neuronal MTs that is observed after incubation with Okadaic acid (HY-N6785). Microtubule stabilizer-1 can be used for the study of Alzheimer’s disease (AD) and related neurodegenerative tauopathies. | ||||||||||||||||||||
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