1 Result for "

Mycobactin-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Mycobactin-IN-1" in MCE Product Catalog:

Cat. No.: HY-145301
CAS No.: 65840-95-1
Target:  

Bacterial

Research Areas:  

Infection

Mycobactin-IN-1, a pyrazoline analogue, is a mycobactin biosynthesis inhibitor against mycobacteria. Mycobactin-IN-1 binds to salicyl-AMP ligase (MbtA), a key enzyme in the mycobactin biosynthetic pathway. Mycobactin-IN-1 inhibits whole-cell drug efflux pumps in M. smegmatis. Mycobactin-IN-1 eradicates intracellularly surviving mycobacteria. Mycobactin-IN-1 shows an excellent in vivo pharmacokinetic profile. Mycobactin-IN-1 can be used for the research of tuberculosis [1].
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