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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
N-methylation
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "N-methylation" in MCE Product Catalog:
1
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
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1
Category:
Alkaloids Pyridine Alkaloids Metabolic Disease Endogenous metabolite Disease Research Fields
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1
1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
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1
1 Cited Publications
Cat. No.: HY-P1108A
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Cat. No.: HY-P10272
CAS No.: 1628323-80-7
Synonyms: PTG-300
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Cat. No.: HY-P10143
CAS No.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Cat. No.: HY-A0248AS
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Cat. No.: HY-W1006754
CAS No.: 1973504-60-7
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NNMT-IN-7 is a nicotinamide N-methyltransferase (NNMT) inhibitor with an IC50 of 505.7 μM against human targets. NNMT-IN-7 inhibits the catalytic activity of NNMT, an enzyme responsible for mediating N-methylation modification of endogenous and exogenous xenobiotics. NNMT-IN-7 can be used in research related to obesity and type 2 diabetes .
Cat. No.: HY-P10563
CAS No.: 2580150-96-3
Synonyms: BHV-1100
Cat. No.: HY-P3066
CAS No.: 77453-01-1
Synonyms: d(CH2)5Tyr(Et)VAVP
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Cat. No.: HY-151738
CAS No.: 1935981-35-3
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Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis . Fmoc-Aeg(N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-P10828
CAS No.: 1260620-30-1
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Cat. No.: HY-124124R
CAS No.: 114-33-0
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Cat. No.: HY-P5514
CAS No.: 409085-42-3
Synonyms: Amylin (22-27) [NMeG24, NMeI26], human (IAPP)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
