114-33-0
114-33-0
Chemical Structure
N-Methylnicotinamide
- CAS No.: 114-33-0
- Formula:C7H8N2O
- Molecular Weight:136.15
IUPAC Name: N-methylnicotinamide
InChIKey: ZYVXHFWBYUDDBM-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN=C1)NC
Biological Activity: N-Methylnicotinamide is an endogenous metabolite with antithrombotic effect. N-Methylnicotinamide via production/release of prostacyclin inhibits arterial thrombosis development. N-Methylnicotinamide is also the N-methylation product from nicotinamide catalyzed by N-methyltransferase within nicotinate and nicotinamide metabolism pathway[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Methylnicotinamide | 99.79% | N-Methylnicotinamide is an endogenous metabolite with antithrombotic effect. N-Methylnicotinamide via production/release of prostacyclin inhibits arterial thrombosis development. N-Methylnicotinamide is also the N-methylation product from nicotinamide catalyzed by N-methyltransferase within nicotinate and nicotinamide metabolism pathway. | ||||||||||||||||||||
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N-Methylnicotinamide (Standard) | 99.97% | N-Methylnicotinamide (Standard) is the analytical standard of N-Methylnicotinamide (HY-124124). This product is intended for research and analytical applications. N-Methylnicotinamide is an endogenous metabolite with antithrombotic effect. N-Methylnicotinamide via production/release of prostacyclin inhibits arterial thrombosis development. N-Methylnicotinamide is also the N-methylation product from nicotinamide catalyzed by N-methyltransferase within nicotinate and nicotinamide metabolism pathway. | ||||||||||||||||||||
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N-Methylnicotinamide-d4 | 98.18% | N-Methylnicotinamide-d4 is the deuterium labeled N-Methylnicotinamide (HY-124124). N-Methylnicotinamide is an endogenous metabolite with antithrombotic effect. N-Methylnicotinamide via production/release of prostacyclin inhibits arterial thrombosis development. N-Methylnicotinamide is also the N-methylation product from nicotinamide catalyzed by N-methyltransferase within nicotinate and nicotinamide metabolism pathway. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-B0329SIsoniazid-d4 -
Similarity Score 0.88
HY-B0150SNicotinamide-d4 -
Similarity Score 0.87
HY-W099339N-Ethylnicotinamide -
Similarity Score 0.87
HY-W012617Nicotinohydrazide -
Similarity Score 0.87
HY-W555601Nicoxamat -
Similarity Score 0.87
HY-W012843SIsonicotinamide-d4 -
Similarity Score 0.87
HY-B1695SMethyl nicotinate-d4 -
Similarity Score 0.86
HY-B0143S2Niacin-d4 -
Similarity Score 0.86
HY-Z4481Sorafenib impurity 4 -
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References
- [1]. Mogielnicki A, et al. N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats. J Physiol Pharmacol. 2007 Sep;58(3):515-27. [Content Brief]
- [2]. Bi HC, et al. N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis. Carcinogenesis. 2014 Oct;35(10):2264-72. [Content Brief]
