2 Results for "

NLRP3/AIM2-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "NLRP3/AIM2-IN-1" in MCE Product Catalog:

Cat. No.: HY-144220
CAS No.: 3033386-91-0
NLRP3/AIM2-IN-1 is an NLRP3/AIM2 inhibitor with an IC50 of 3.136 μM against NLRP3-dependent pyroptosis. NLRP3/AIM2-IN-1 inhibits IL-1β secretion triggered by NLRP3 inflammasome activation. NLRP3/AIM2-IN-1 exhibits moderate anti-pyroptotic activity. NLRP3/AIM2-IN-1 does not inhibit NLRC4 inflammasome activation. NLRP3/AIM2-IN-1 can be used for studying inflammasome-mediated inflammatory diseases .
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Cat. No.: HY-161669
Research Areas:  

Inflammation/Immunology

NLRP3-IN-40 (compound 32) is an inhibitor of the inflammasome NLRP3, which blocks NLRP3 activation induced by multiple agonists without altering NLRC4 or AIM2 inflammasomes .
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