2 Results for "

Nampt-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Nampt-IN-5" in MCE Product Catalog:

Cat. No.: HY-130606
CAS No.: 2380013-17-0
Purity:  98.02%
Target:  

NAMPT Cytochrome P450

Research Areas:  

Cancer

Nampt-IN-5 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-5 also inhibits CYP3A4 activity and has cellular IC50s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively .
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Cat. No.: HY-162269
CAS No.: 3041005-21-1
Target:  

NAMPT

Research Areas:  

Inflammation/Immunology

Nampt activator-5 is a NAMPT activator with a KD value of 6.19 μM. Nampt activator-5 activates the rate-limiting enzyme in NAD + biosynthesis and promotes NAD + production. Nampt activator-5 delays the senescence process of senescent hepatocytes, extends the lifespan of *Caenorhabditis elegans*, and alleviates age-related dysfunction and abnormal biomarkers in naturally aged mice. Nampt activator-5 can be used in aging research .
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