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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Netupitant hydrochloride
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Netupitant hydrochloride" in MCE Product Catalog:
Cat. No.: HY-16347
CAS No.: 290296-54-7
Synonyms: CID 6451149 hydrochloride
Target:
Research Areas:
Netupitant hydrochloride (CID 6451149 hydrochloride) is a blood-brain barrier penetrable, orally active NK1 receptor inhibitor with a Ki of 0.95 nM (CHO cells) against the human receptor. Netupitant hydrochloride antagonizes the effects induced by Substance P, inhibits the maximal response of Substance P with a long-lasting action, and suppresses NK1 agonist-induced behaviors in mice and gerbils. Netupitant hydrochloride reduces the frequency of bladder contractions, prolongs contraction intervals, decreases basal pressure at high doses, and acts on the afferent branch of the micturition reflex. Netupitant hydrochloride can be used in research related to overactive bladder, chemotherapy-induced nausea and vomiting, post-operative nausea and vomiting, anxiety disorders, and depression .
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Target:
Netupitant (CID 6451149) is a blood-brain barrier penetrable, orally active NK1 receptor inhibitor with a Ki of 0.95 nM (CHO cells) against the human receptor. Netupitant antagonizes the effects induced by Substance P, inhibits the maximal response of Substance P with a long-lasting action, and suppresses NK1 agonist-induced behaviors in mice and gerbils. Netupitant reduces the frequency of bladder contractions, prolongs contraction intervals, decreases basal pressure at high doses, and acts on the afferent branch of the micturition reflex. Netupitant can be used in research related to overactive bladder, chemotherapy-induced nausea and vomiting, post-operative nausea and vomiting, anxiety disorders, and depression .
Synonyms: ProNetupitant chloride monohydrochloride
Target:
Research Areas:
Fosnetupitant chloride monohydrochloride (Pronetupitant chloride monohydrochloride) is an NK1 antagonist with pKi values of 9.5, 6.1 for human NK1 and NK3 receptor, respectively. Fosnetupitant chloride monohydrochloride is a methylene phosphate prodrug of Netupitant .
Cat. No.: HY-16346S
CAS No.: 2070015-31-3
Synonyms: CID-6451149-d6
Cat. No.: HY-G0010
CAS No.: 290296-72-9
Synonyms: N-desmethyl Netupitant
Target:
Research Areas:
N-desmethyl Netupitant is a metabolite of Netupitant, which is an antiemitic drug.
Cat. No.: HY-17615
CAS No.: 1703748-89-3
Synonyms: ProNetupitant
Target:
Research Areas:
Fosnetupitant (Pronetupitant) a methylene phosphate proagent of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pKi of 9.5 for human NK1 receptor .
Cat. No.: HY-G0012
CAS No.: 910808-12-7
Synonyms: Monohydroxy Netupitant
Target:
Research Areas:
Monohydroxy Netupitant is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist.
Cat. No.: HY-G0011
CAS No.: 910808-11-6
Synonyms: Netupitant N-oxide
Target:
Research Areas:
Netupitant N-oxide is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist.
Cat. No.: HY-G0012S
CAS No.: 2070015-07-3
Cat. No.: HY-G0010S
CAS No.: 2070015-21-1
Cat. No.: HY-G0011S
CAS No.: 2070015-12-0
Cat. No.: HY-16346R
CAS No.: 290297-26-6
Synonyms: CID 6451149 (Standard)
Research Areas:
Netupitant (Standard) is the analytical standard of Netupitant. This product is intended for research and analytical applications. Netupitant (CID-6451149) is a highly potent, selective and orally active neurokinin-1 (NK1) receptor antagonist with a Ki of 0.95 nM for hNK1 in CHO cells. Netupitant has antiemetic affect .
Cat. No.: HY-W758677A
Synonyms: ProNetupitant-d6 dihydrochloride
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
