1643757-72-5
Chemical Structure
Fosnetupitant chloride monohydrochloride
Synonym(s): Pronetupitant chloride monohydrochloride
- CAS No.: 1643757-72-5
- Formula:C31H37Cl2F6N4O5P
- Molecular Weight:761.52
IUPAC Name: 4-(5-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(o-tolyl)pyridin-2-yl)-1-methyl-1-((phosphonooxy)methyl)piperazin-1-ium chloride hydrochloride
InChIKey: LBTQUZNIWCWBNN-UHFFFAOYSA-N
SMILES: O=C(C(C)(C)C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N(C)C2=CN=C(N3CC[N+](COP(O)(O)=O)(CC3)C)C=C2C4=C(C)C=CC=C4.[H]Cl.[Cl-]
Biological Activity: Fosnetupitant chloride monohydrochloride (Pronetupitant chloride monohydrochloride) is an NK1 antagonist with pKi values of 9.5, 6.1 for human NK1 and NK3 receptor, respectively. Fosnetupitant chloride monohydrochloride is a methylene phosphate prodrug of Netupitant[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fosnetupitant chloride monohydrochloride | 98.58% | Fosnetupitant chloride monohydrochloride (Pronetupitant chloride monohydrochloride) is an NK1 antagonist with pKi values of 9.5, 6.1 for human NK1 and NK3 receptor, respectively. Fosnetupitant chloride monohydrochloride is a methylene phosphate prodrug of Netupitant. | ||||||||||||||||||||
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Similarity Score 0.94
HY-17615Fosnetupitant -
Similarity Score 0.83
HY-G0011Netupitant metabolite Netupitant N-oxide -
Similarity Score 0.81
HY-16346RNetupitant (Standard) -
Similarity Score 0.80
HY-G0010Netupitant metabolite N-desmethyl Netupitant -
Similarity Score 0.78
HY-19670Befetupitant -
Similarity Score 0.76
HY-G0012Netupitant metabolite Monohydroxy Netupitant -
Similarity Score 0.72
HY-G0011SNetupitant N-oxide-d6 -
Similarity Score 0.70
HY-16346SNetupitant-d6 -
Similarity Score 0.69
HY-G0010SN-desmethyl Netupitant-d6 -
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