Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
OP
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "OP" in MCE Product Catalog:
5
3
Target:
Áreas de investigación:
Solithromycin (CEM-101) is an orally bioavailable, effective antimicrobial agent, with IC50s for inhibition of cell viability, protein synthesis, and growth rate are 7.5 ng/mL, 40 ng/mL, and 125 ng/mL for Streptococcus pneumonia, Staphylococcus aureus, and Haemophilus influenzae, respectively. Solithromycin binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis .
3
3 Cited Publications
Referencia número: HY-P71786
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Spp1; Eta-1; OP; Spp-1; OsteOPontin; 2AR; MinOPontin; Secreted phosphOProtein 1; SPP-1
Species:
Source:
2
2 Cited Publications
Synonyms: OP0595 free acid
Target:
Áreas de investigación:
Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and C β-lactamases. Nacubactam acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs. Nacubactam potentiates the antimicrobial activities of Piperacillin (HY-B1923), Cefepime (HY-B0692), and Meropenem (HY-13678) against CTX-M-15-positive Escherichia coli and KPC-positive Klebsiella pneumoniae .
2
1
1 Cited Publications
Referencia número: HY-N1499
No. CAS: 13133-07-8
Category:
Polysaccharides Rubiaceae Metabolic Disease Plants Morinda officinalis How Disease Research Fields Saccharides
Target:
1
1 Cited Publications
Referencia número: HY-B0683
No. CAS: 74397-12-9
Synonyms: 17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206
Target:
Áreas de investigación:
Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research .
Synonyms: OP-1250
Target:
Áreas de investigación:
Palazestrant is an antiestrogen and antineoplastic agent. Palazestrant can completely inhibit the activity of 17b-estradiol (E2) with IC50 value of 6.4 nM, and inhibit the proliferation of MCF7 and CAMA-1 cells with IC50 value of 1.4-1.6 nM. Palazestrant can inhibit ER +/HER2 + cancer .
Referencia número: HY-W009004
No. CAS: 13184-14-0
Synonyms: Lys-Lys-Lys; H-Lys-Lys-Lys-OH
Target:
Áreas de investigación:
Referencia número: HY-W016188
No. CAS: 830-81-9
Target:
Áreas de investigación:
1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .
Referencia número: HY-165607S
No. CAS: 3058199-58-6
Referencia número: HY-RS16219
Target:
Áreas de investigación:
SPP1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for SPP1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-P1302
No. CAS: 178249-41-7
Target:
Áreas de investigación:
YCH1899 is an orally active PARP inhibitor, with an IC50< 0.001 nM for PARP1/2. YCH1899 exhibits distinct antiproliferation activity against Olaparib (HY-10162)-resistant and Talazoparib (HY-16106)-resistant Capan-1 cells (Capan-1/OP and Capan-1/TP cells) , with IC50 values of 0.89 and 1.13 nM, respectively. YCH1899 has acceptable pharmacokinetic properties in rats .
Referencia número: HY-P1317A
Target:
Áreas de investigación:
Target:
Áreas de investigación:
OP-5244 is a potent and orally active inhibitor of CD73, with an IC50 of 0.25 nM. OP-5244 reverses immunosuppression through blocking of adenosine production, and has the potential for the cancer research .
Referencia número: HY-N1961
No. CAS: 38971-41-4
Synonyms: OP-B
Referencia número: HY-W016188R
No. CAS: 830-81-9
Áreas de investigación:
1-Naphthyl acetate is an attractive chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity. 1-Naphthyl acetate has the potential to detect organophosphorus pesticide (OP) poisoning .
Referencia número: HY-P10345
No. CAS: 732984-81-5
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
