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Results for "

Ornithine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Ornithine decarboxylase (ODC) (4) Acetyl-CoA Carboxylase (1) ADC Linker (1) Adrenergic Receptor (1) Akt (2) Amino Acid Decarboxylase (1) Amino Acid Derivatives (1) Aminotransferases (Transaminases) (1) Androgen Receptor (1) Antibiotic (2) Apoptosis (3) Arginase (3) Bacterial (5) Biochemical Assay Reagents (13) Carboxypeptidase (1) CDK (1) Drug Derivative (4) Drug Intermediate (4) Drug Metabolite (1) Endogenous Metabolite (27) Environmental Pollutants (1) Fungal (2) GABA Receptor (1) GHR (1) HCV (1) Herbicide (1) Histone Methyltransferase (2) HSV (1) Insulin Receptor (1) Isotope-Labeled Compounds (6) Microtubule/Tubulin (1) Nucleoside Antimetabolite/Analog (1) OAT (1) PAK (1) Parasite (9) PKC (2) Prolyl Endopeptidase (PREP) (1) RAR/RXR (1) Reference Standards (12)
By Research Areas:	Cancer (24) Cardiovascular Disease (2) Endocrinology (1) Infection (10) Inflammation/Immunology (7) Metabolic Disease (32) Neurological Disease (5)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: Ornithine decarboxylase (ODC)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0744

Eflornithine Maximum Cited Publications 21 Publications Verification DFMO; MDL71782; RMI71782; α-difluoromethylOrnithine	Parasite	Infection Cancer
Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

HY-B1352

L-Ornithine Maximum Cited Publications 9 Publications Verification (S)-2,5-Diaminopentanoic acid	Arginase Endogenous Metabolite	Metabolic Disease
L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective .

HY-N0391

L-Citrulline 5+ Cited Publications	Endogenous Metabolite	Others
L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-B0744B

Eflornithine hydrochloride hydrate Maximum Cited Publications 21 Publications Verification DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylOrnithine hydrochloride hydrate	Parasite	Cancer
Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .

HY-101938

Sinefungin 4 Publications Verification Adenosyl-Ornithine; A-9145; Antibiotic 32232RP	Histone Methyltransferase Fungal Antibiotic Parasite	Infection Inflammation/Immunology
Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication . Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation .

HY-N0240

Herbacetin 5 Publications Verification	Ornithine decarboxylase (ODC)	Cancer
Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .

HY-W017018

*L-Ornithine* hydrochloride** Maximum Cited Publications 9 Publications Verification	Endogenous Metabolite	Metabolic Disease
L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-124617A

AMXT-1501 tetrahydrochloride 5+ Cited Publications	Apoptosis Bacterial	Infection Inflammation/Immunology Cancer
AMXT-1501 tetrahydrochloride is a Bacterial agent and polyamine transport system inhibitor. AMXT-1501 tetrahydrochloride targets membrane phospholipids and exhibits antibacterial activity against a variety of Gram-positive and Gram-negative multidrug-resistant bacteria . AMXT-1501 tetrahydrochloride inhibits capsular biosynthesis in Streptococcus pneumoniae . AMXT-1501 tetrahydrochloride targets ornithine decarboxylase and polyamines to inhibit the proliferation of neuroblastoma cells . AMXT-1501 tetrahydrochloride in combination with DFMO (HY-B0744) induces Apoptosis in neuroblastoma cells. AMXT-1501 tetrahydrochloride is applicable to research related to multidrug-resistant bacterial infections, pneumococcal infections, Streptococcus pneumoniae infections, and neuroblastoma .

HY-126436A

*Poly-L-ornithine* hydrobromide (MW 30000-70000)** L-Ornithine homopolymer hydrobromide (MW 30000-70000)	Biochemical Assay Reagents	Neurological Disease
Poly-L-ornithine hydrobromide (MW 30000-70000) is a poly-lysine derivative with a molecular weight of 30000-70000. Poly-L-ornithine hydrobromide (MW 30000-70000) binds to the surface of cell culture vessels through positively charged amino acid residues to form a coating that promotes cell adhesion and provides cells with a matrix environment required for growth. Poly-L-ornithine hydrobromide (MW 30000-70000) is used as a coating agent in cell culture and can be used for the study of primary culture of neurons (such as dopaminergic neurons and oligodendrocytes) .

HY-B0744A

Eflornithine hydrochloride Maximum Cited Publications 21 Publications Verification DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylOrnithine hydrochloride	Parasite	Infection Cancer
Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

HY-124617

AMXT-1501 5+ Cited Publications	Apoptosis Bacterial	Infection Cancer
AMXT-1501 is a Bacterial agent and polyamine transport system inhibitor. AMXT-1501 targets membrane phospholipids and exhibits antibacterial activity against a variety of Gram-positive and Gram-negative multidrug-resistant bacteria . AMXT-1501 inhibits capsular biosynthesis in Streptococcus pneumoniae . AMXT-1501 targets ornithine decarboxylase and polyamines to inhibit the proliferation of neuroblastoma cells . AMXT-1501 in combination with DFMO (HY-B0744) induces Apoptosis in neuroblastoma cells. AMXT-1501 is applicable to research related to multidrug-resistant bacterial infections, pneumococcal infections, Streptococcus pneumoniae infections, and neuroblastoma .

HY-113080

N-Acetylornithine 1 Publications Verification	Others	Metabolic Disease
N-Acetylornithine is a precursor of ornithine. N-Acetylornithine is associated with type 2 diabetes .

HY-N0391S5

L-Citrulline-d7	Isotope-Labeled Compounds Endogenous Metabolite	Others
L-Citrulline-d₇ is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-A0282

*L-Ornithine* L-aspartate**	Amino Acid Derivatives	Metabolic Disease Inflammation/Immunology
L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids with oral activity: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. L-Ornithine L-aspartate also improves mitochondrial functions .

HY-21088

3-Amino-2-piperidinone Cyclo-Ornithine	Drug Intermediate	Others
3-Amino-2-piperidinone (Cyclo-ornithine) is a cyclic ornithine analogue and can be used as drug intermediate .

HY-129476

L-Canaline	Parasite Endogenous Metabolite	Infection Cancer
L-Canaline is a nonprotein amino acid stored in many leguminous plants. L-Canaline is a cytotoxic metabolite catalyzed by L-canavanine and its arginase. L-Canaline is a potent and irreversible inhibitor of ornithine aminotransferase. L-Canaline inhibits the growth of the malaria parasite *Plasmodium falciparum* with an IC₅₀ of 297 nM. L-Canaline has anticancer and antiproliferative effects .

HY-34516

*D-Ornithine* hydrochloride** (R)-Ornithine hydrochloride	Endogenous Metabolite Bacterial	Metabolic Disease
D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .

HY-W017018S2

*L-Ornithine-1,2,3,4,5-13C5 hydrochloride*	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Ornithine-1,2,3,4,5- ¹³C₅ (hydrochloride) is the ¹³C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-132822

Ivospemin SBP-101	Drug Derivative	Cancer
Ivospemin (SBP-101) is an antineoplastic spermine analog. Ivospemin has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin is promising for research of cancers .

HY-100983

Protein kinase inhibitor H-7 dihydrochloride	PKC	Cancer
Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) .

HY-N0391S4

L-Citrulline-d4	Endogenous Metabolite	Others
L-Citrulline-d₄ is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-B0744D

L-Eflornithine monohydrochloride L-DFMO monohydrochloride; ; L-RMI71782 monohydrochloride; L-α-difluoromethylOrnithine monohydrochloride	Parasite	Cancer
L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a K_D of 1.3±0.3 µM, and a K_inact of 0.15±0.03 min ^-1 .

HY-154021A

5-Fluoromethylornithine dihydrochloride 5-FMOrn dihydrochloride	OAT	Metabolic Disease
5-Fluoromethylornithine (5-FMOrn) dihydrochloride is a specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT). 5-Fluoromethylornithine dihydrochloride can be used in the study of gyrate atrophy of choroid and retina .

HY-B1713A

*DL-Ornithine* hydrochloride** DL-(±)-Ornithine hydrochloride	Endogenous Metabolite	Metabolic Disease
DL-Ornithine (DL-(±)-Ornithine) hydrochloride is an amino acid and also a urea cycle promoter. DL-Ornithine hydrochloride has the characteristics of low metabolic rate and rapid excretion, and only the L-enantiomer undergoes decarboxylation. In mice inoculated with L-1210 leukemia cells, DL-Ornithine hydrochloride is excreted in urine in its original form, and its conversion to carbon dioxide within 24 h is negligible. DL-Ornithine hydrochloride is mainly used in the urea cycle to eliminate excess nitrogen in the body and protect the kidneys .

HY-131514

*L-Ornithine* 2-oxoglutarate** Ornithine α-ketoglutarate; OKG	Insulin Receptor GHR	Inflammation/Immunology
L-Ornithine 2-oxoglutarate (Ornithine alpha-ketoglutarate) is a nutritional compound that is a salt of amino acids with antioxidant and anti-inflammatory effects. L-Ornithine 2-oxoglutarate stimulates the production of insulin and growth hormone, and promotes intracellular amino acid transport and protein synthesis .

HY-W017018S

*L-Ornithine-d6 hydrochloride*	Endogenous Metabolite	Metabolic Disease
L-Ornithine-d₆ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W017018S4

*L-Ornithine-d7 hydrochloride*	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Ornithine-d₇ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-126436C

*Poly-L-ornithine* hydrobromide (MW 5000-15000)** L-Ornithine homopolymer hydrobromide (MW 5000-15000)	Biochemical Assay Reagents	Others
Poly-L-ornithine (hydrobromide) (MW 5000-15000) (L-Ornithine homopolymer (hydrobromide) (MW 5000-15000)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W017018B

*L-Ornithine* monohydrochloride,suitable for cell culture**	Biochemical Assay Reagents	Others
L-Ornithine monohydrochloride, suitable for cell culture is a non-proteinogenic amino acid that is mainly used in the urea cycle to remove excess nitrogen from the body and can be used for cell culture .

HY-N0391S3

L-Citrulline-13C	Endogenous Metabolite	Others
L-Citrulline- ¹³C is the ¹³C-labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-N0391R

L-Citrulline (Standard)	Reference Standards Endogenous Metabolite	Others
L-Citrulline (Standard) is the analytical standard of L-Citrulline. This product is intended for research and analytical applications. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-P2758

Diamine oxidase DAO	Biochemical Assay Reagents	Metabolic Disease Inflammation/Immunology Cancer
Diamine oxidase (DAO) is an orally active enzyme. Diamine oxidase catalyzes oxidative deamination of various polyamines. Diamine oxidase degrades histamine and polyamines to maintain the metabolic balance of amines in the body. Diamine oxidase is a key regulatory enzyme in rapidly proliferating tissues such as bone marrow and intestinal mucosa. Diamine oxidase can be used in research related to intestinal diseases, small bowel transplant rejection, histamine intolerance, and other conditions .

HY-126436D

*Poly-L-ornithine* hydrochloride (MW 15000-30000)** L-Ornithine homopolymer hydrochloride (MW 15000-30000)	Biochemical Assay Reagents	Metabolic Disease Endocrinology
Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1). Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases .

HY-W017018S5

*L-Ornithine-15N2 hydrochloride*	Endogenous Metabolite	Metabolic Disease
L-Ornithine- ¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-P3190

Arginase, Microorganism (immobilized) L-Arginine amidinase	Endogenous Metabolite	Metabolic Disease
Arginase, Microorganism immobilized (L-Arginine amidinase) is an enzyme of the urea cycle. Arginase catalyzes the hydrolysis of L-arginine to L-ornithine and urea .

HY-W023493

DL-Allylglycine 2-Aminopent-4-enoic acid	Amino Acid Decarboxylase	Neurological Disease
DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures .

HY-N15001

Gabaculine	GABA Receptor	Neurological Disease
Gabaculine is an amino acid neurotoxin and blood-brain barrier-permeable GABA transaminase inhibitor, with an IC₅₀ of 1 μM in beef and Pseudomonas ovalis. Gabaculine elevates endogenous synaptic and brain GABA levels and enhances GABA activity. Gabaculine induces sedation, hypothermia, loss of righting reflex, and prevents convulsions in mice. Gabaculine is applicable to research related to neurological disorders .

HY-W017018R

*L-Ornithine* hydrochloride (Standard)**	Reference Standards Endogenous Metabolite	Metabolic Disease
L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-113080R

N-Acetylornithine (Standard)	Reference Standards Endogenous Metabolite Biochemical Assay Reagents	Metabolic Disease
N-Acetylornithine (Standard) is an analytical standard for N-Acetylornithine. This product is intended for research and analytical applications. N-Acetylornithine is a precursor of ornithine. N-Acetylornithine is associated with type 2 diabetes .

HY-B0744BR

Eflornithine hydrochloride hydrate (Standard) DFMO hydrochloride hydrate (Standard); MDL-71782 hydrochloride hydrate (Standard); RMI-71782 hydrochloride hydrate (Standard); α-difluoromethylOrnithine hydrochloride hydrate (Standard)	Reference Standards Parasite	Cancer
Eflornithine (hydrochloride hydrate) (Standard) is the analytical standard of Eflornithine (hydrochloride hydrate). This product is intended for research and analytical applications. Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .

HY-151748

N3-L-Orn(Fmoc)-OH	ADC Linker	Others
N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-B2007

Fluazifop-P-butyl	Environmental Pollutants Acetyl-CoA Carboxylase Herbicide	Metabolic Disease Inflammation/Immunology
Fluazifop-P-butyl is an orally active herbicide and ACCase inhibitor. Fluazifop-P-butyl blocks the formation of malonyl-CoA, disrupts lipid synthesis in sensitive plants, and exhibits concentration-dependent phytotoxicity to non-target maize seedlings. Fluazifop-P-butyl induces oxidative stress in male Wistar rats, impairs their liver and kidney functions, and disrupts testicular function .

HY-W017018S3

*L-Ornithine-d2 hydrochloride*	Endogenous Metabolite	Metabolic Disease
L-Ornithine-d₂ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-126436B

*Poly-L-ornithine* hydrobromide (MW>100000)** L-Ornithine homopolymer hydrobromide (MW>100000)	Biochemical Assay Reagents	Others
Poly-L-ornithine (hydrobromide) (MW>100000) (L-Ornithine homopolymer (hydrobromide) (MW>100000)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-160843

NCAO	Apoptosis	Cancer
N-ω-chloroacetyl-L-ornithine (NCAO) is a potent reversible competitive ornithine decarboxylase (ODC) inhibitor that exerts cytotoxic and antiproliferative effects on tumor cell lines with EC₅₀ values ranging from 1 to 50.6 µM. NCAO induces tumor cell Apoptosis and inhibits tumor cell migration in vitro. NCAO also exhibits a potent antitumor activity against both solid and ascitic tumors in a mouse model using the myeloma (Ag8) cell line. NCAO is promising for research of antitumor agents .

HY-B0744C

L-Eflornithine L-DFMO; L-RMI71782; L-α-difluoromethylOrnithine	Parasite	Cancer
L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a K_D of 1.3±0.3 µM, and a K_inact of 0.15±0.03 min ^-1 .

HY-W364575

Methyl-4-oxoretinoate	Drug Derivative	Cancer
Methyl-4-oxoretinoate is a derivative of Retinoic acid (HY-14649). Methyl-4-oxoretinoate inhibits TPA (HY-18739)-induced ornithine decarboxylase (ODC) activity, and carcinogen-induced papillomas in mouse skin .

HY-W011092

Boc-Orn(Z)-OH Nα-Boc-Nδ-Cbz-L-Ornithine	Biochemical Assay Reagents	Others
Boc-Orn(Z)-OH (Nα-Boc-Nδ-Cbz-L-ornithine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-132822A

Ivospemin hydrochloride SBP-101 hydrochloride	Drug Derivative	Cancer
Ivospemin (SBP-101) hydrochloride is an antineoplastic spermine analog. Ivospemin hydrochloride has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo. Ivospemin hydrochloride shows modest induction of polyamine catabolism, but stronger repression of ornithine decarboxylase activity. Ivospemin hydrochloride is promising for research of cancers .

HY-113289R

Brassicasterol (Standard)	Akt Androgen Receptor Bacterial Drug Metabolite HSV Reference Standards	Infection Cardiovascular Disease Neurological Disease Cancer
L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

Cat. No.	Product Name	Type

HY-126436A

Poly-L-ornithine hydrobromide (MW 30000-70000)

L-Ornithine homopolymer hydrobromide (MW 30000-70000)

Biochemical Assay Reagents

Poly-L-ornithine hydrobromide (MW 30000-70000) is a poly-lysine derivative with a molecular weight of 30000-70000. Poly-L-ornithine hydrobromide (MW 30000-70000) binds to the surface of cell culture vessels through positively charged amino acid residues to form a coating that promotes cell adhesion and provides cells with a matrix environment required for growth. Poly-L-ornithine hydrobromide (MW 30000-70000) is used as a coating agent in cell culture and can be used for the study of primary culture of neurons (such as dopaminergic neurons and oligodendrocytes) .

HY-B1713A

DL-Ornithine hydrochloride

DL-(±)-Ornithine hydrochloride

Biochemical Assay Reagents

DL-Ornithine (DL-(±)-Ornithine) hydrochloride is an amino acid and also a urea cycle promoter. DL-Ornithine hydrochloride has the characteristics of low metabolic rate and rapid excretion, and only the L-enantiomer undergoes decarboxylation. In mice inoculated with L-1210 leukemia cells, DL-Ornithine hydrochloride is excreted in urine in its original form, and its conversion to carbon dioxide within 24 h is negligible. DL-Ornithine hydrochloride is mainly used in the urea cycle to eliminate excess nitrogen in the body and protect the kidneys .

HY-126436C

*Poly-L-ornithine* hydrobromide (MW 5000-15000)** L-Ornithine homopolymer hydrobromide (MW 5000-15000)	Biochemical Assay Reagents
Poly-L-ornithine (hydrobromide) (MW 5000-15000) (L-Ornithine homopolymer (hydrobromide) (MW 5000-15000)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W017018B

*L-Ornithine* monohydrochloride,suitable for cell culture**	Biochemical Assay Reagents
L-Ornithine monohydrochloride, suitable for cell culture is a non-proteinogenic amino acid that is mainly used in the urea cycle to remove excess nitrogen from the body and can be used for cell culture .

HY-126436D

Poly-L-ornithine hydrochloride (MW 15000-30000)

L-Ornithine homopolymer hydrochloride (MW 15000-30000)

Biochemical Assay Reagents

Poly-L-ornithine hydrochloride (MW 15000-30000) is a polycationic homopolymer composed of L-ornithine. Poly-L-ornithine hydrochloride (MW 15000-30000) adsorbs negatively charged species through electrostatic interactions. Poly-L-ornithine hydrochloride (MW 15000-30000) can be used as a key component of polyelectrolyte complexes to construct core-shell structure carriers to achieve controlled delivery of growth factors (such as rhBMP-2, FGF-1). Poly-L-ornithine hydrochloride (MW 15000-30000) is used in the study of diabetes and bone regeneration related diseases .

HY-126436B

*Poly-L-ornithine* hydrobromide (MW>100000)** L-Ornithine homopolymer hydrobromide (MW>100000)	Biochemical Assay Reagents
Poly-L-ornithine (hydrobromide) (MW>100000) (L-Ornithine homopolymer (hydrobromide) (MW>100000)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

Cat. No.	Product Name	Target	Research Area

HY-W023493

DL-Allylglycine 2-Aminopent-4-enoic acid	Amino Acid Decarboxylase	Neurological Disease
DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1352

L-Ornithine Maximum Cited Publications 9 Publications Verification (S)-2,5-Diaminopentanoic acid	Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder Source Classification	Arginase Endogenous Metabolite
L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective .

HY-N0391

L-Citrulline 5+ Cited Publications	Classification of Application Fields Disease markers Other Diseases Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-N0240

Herbacetin 5 Publications Verification	Flavonols Structural Classification Flavonoids Linum usitatissimum Linn. Classification of Application Fields Linaceae Phenols Polyphenols Plants Disease Research Fields Source Classification Cancer	Ornithine decarboxylase (ODC)
Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .

HY-W017018

*L-Ornithine* hydrochloride** Maximum Cited Publications 9 Publications Verification	Microorganisms Classification of Application Fields Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-113080

N-Acetylornithine 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Others
N-Acetylornithine is a precursor of ornithine. N-Acetylornithine is associated with type 2 diabetes .

HY-21088

3-Amino-2-piperidinone Cyclo-Ornithine	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Drug Intermediate
3-Amino-2-piperidinone (Cyclo-ornithine) is a cyclic ornithine analogue and can be used as drug intermediate .

HY-129476

L-Canaline	Infection other families Classification of Application Fields Amino acids Plants Endogenous metabolite Disease Research Fields Source Classification	Parasite Endogenous Metabolite
L-Canaline is a nonprotein amino acid stored in many leguminous plants. L-Canaline is a cytotoxic metabolite catalyzed by L-canavanine and its arginase. L-Canaline is a potent and irreversible inhibitor of ornithine aminotransferase. L-Canaline inhibits the growth of the malaria parasite *Plasmodium falciparum* with an IC₅₀ of 297 nM. L-Canaline has anticancer and antiproliferative effects .

HY-34516

*D-Ornithine* hydrochloride** (R)-Ornithine hydrochloride	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Bacterial
D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .

HY-N0391R

L-Citrulline (Standard)	Structural Classification Disease markers Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
L-Citrulline (Standard) is the analytical standard of L-Citrulline. This product is intended for research and analytical applications. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-N15001

Gabaculine	Structural Classification Natural Products Microorganisms Source Classification	GABA Receptor
Gabaculine is an amino acid neurotoxin and blood-brain barrier-permeable GABA transaminase inhibitor, with an IC₅₀ of 1 μM in beef and Pseudomonas ovalis. Gabaculine elevates endogenous synaptic and brain GABA levels and enhances GABA activity. Gabaculine induces sedation, hypothermia, loss of righting reflex, and prevents convulsions in mice. Gabaculine is applicable to research related to neurological disorders .

HY-W017018R

*L-Ornithine* hydrochloride (Standard)**	Structural Classification Microorganisms Amino acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-113080R

N-Acetylornithine (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Biochemical Assay Reagents
N-Acetylornithine (Standard) is an analytical standard for N-Acetylornithine. This product is intended for research and analytical applications. N-Acetylornithine is a precursor of ornithine. N-Acetylornithine is associated with type 2 diabetes .

HY-113289R

Brassicasterol (Standard)	Animals Steroids Source Classification	Akt Androgen Receptor Bacterial Drug Metabolite HSV Reference Standards
L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective .

HY-34516R

*D-Ornithine* hydrochloride (Standard)** (R)-Ornithine hydrochloride (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite Bacterial Reference Standards
D-Ornithine (hydrochloride) (Standard) is the analytical standard of D-Ornithine (hydrochloride). This product is intended for research and analytical applications. D-Ornithine ((R)-Ornithine) hydrochloride is a constituent of bacterial cell wall. D-Ornithine hydrochloride promotes the production of L-arginine (HY-N0455). D-Ornithine hydrochloride enhances the expression of pyrrolysine-containing proteins .

HY-21088R

3-Amino-2-piperidinone (Standard) Cyclo-Ornithine (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Drug Intermediate
3-Amino-2-piperidinone (Standard) is the analytical standard of 3-Amino-2-piperidinone. This product is intended for research and analytical applications. 3-Amino-2-piperidinone (Cyclo-ornithine) is a cyclic ornithine analogue and can be used as drug intermediate .

HY-N14218

Eurystatin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Prolyl Endopeptidase (PREP)
Eurystatin A is a prolyl endopeptidase inhibitor, L-Leucine and L-Ornithine are the direct precursors of the L-Leucine and L-Ornithine moieties of eurystatins A .

HY-N0240R

Herbacetin (Standard)	Flavonols Structural Classification Flavonoids Linum usitatissimum Linn. Linaceae Phenols Polyphenols Plants Source Classification	Reference Standards Others
Herbacetin (Standard) is the analytical standard of Herbacetin. This product is intended for research and analytical applications. Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects . Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis .

HY-N8063

γ-Glutamylornithine	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite
γ-Glutamylornithine is the urine excreta of patients with HHH syndrome (hyperuricemia, hyperaminemia, and hypercitrullinuria) and rotary atrophy associated with hyperuricemia. Increased levels of endogenous ornithine increase levels of γ-Glutamylornithine in the urine .

HY-N8063R

γ-Glutamylornithine (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
γ-Glutamylornithine is the urine excreta of patients with HHH syndrome (hyperuricemia, hyperaminemia, and hypercitrullinuria) and rotary atrophy associated with hyperuricemia. Increased levels of endogenous ornithine increase levels of γ-Glutamylornithine in the urine .

HY-B1713

*Ornithine* (±)-Ornithine	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite Ornithine decarboxylase (ODC) Drug Intermediate
Ornithine ((±)-Ornithine) is a non-essential amino acid. Ornithine is an intermediate in urea cycle and acts as a substrate for these rate limiting enzymes ornithine transcarbomylase, ornithine aminotransferase and ornithine decarboxylase producing citrulline, proline and polyamines, respectively. Ornithine can be used in the research of hyperornithinemia, hyperammonemia, and cancer .

HY-180706

N2-Succinyl-L-ornithine	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
N2-Succinyl-L-ornithine is a nucleoside metabolite.

HY-23964

4-Methylthio-2-oxobutanoic acid MTOB	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Ornithine decarboxylase (ODC)
4-Methylthio-2-oxobutanoic acid (MTOB) is an ornithine decarboxylase inhibitor. 4-Methylthio-2-oxobutanoic acid reduces ornithine decarboxylase protein levels and enzymatic activity. 4-Methylthio-2-oxobutanoic acid is formed in cells in the Met salvage pathway from methylthioadenosine. 4-Methylthio-2-oxobutanoic acid inhibits cancer cells growth. 4-Methylthio-2-oxobutanoic acid can be used for the research of cancer .

Species:	Human (2)
Tag:	SUMO (1) T7 (1) His (2) Myc (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71109

	ODC1 Protein, Human (His-T7) 1 Publications Verification Ornithine decarboxylase; ODC1;	Human	E. coli
	ODC (ornithine decarboxylase) is the rate-limiting enzyme in polyamine biosynthesis, catalyzing the conversion of ornithine to putrescine, a precursor of polyamines such as spermidine and spermine, which influence cell proliferation and various cellular processes. ODC1 Protein, Human (His-T7) is the recombinant human-derived ODC1 protein, expressed by E. coli , with N-T7, C-6*His labeled tag.

HY-P702593

	ODC1 Protein, Human (His-SUMO, Myc) Ornithine decarboxylase; ODC1;	Human	E. coli
	ODC (ornithine decarboxylase) is the rate-limiting enzyme in polyamine biosynthesis, catalyzing the conversion of ornithine to putrescine, a precursor of polyamines such as spermidine and spermine, which influence cell proliferation and various cellular processes. ODC1 Protein, Human (His-SUMO, Myc) is the recombinant human-derived ODC1, expressed by E. coli, with N-10*His, C-Myc, N-SUMO labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-N0391S5

L-Citrulline-d7
L-Citrulline-d₇ is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-W017018S2

*L-Ornithine-1,2,3,4,5-13C5 hydrochloride*
L-Ornithine-1,2,3,4,5- ¹³C₅ (hydrochloride) is the ¹³C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-N0391S4

L-Citrulline-d4
L-Citrulline-d₄ is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-W017018S

*L-Ornithine-d6 hydrochloride*
L-Ornithine-d₆ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W017018S4

*L-Ornithine-d7 hydrochloride*
L-Ornithine-d₇ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-N0391S3

L-Citrulline-13C
L-Citrulline- ¹³C is the ¹³C-labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-W017018S5

*L-Ornithine-15N2 hydrochloride*
L-Ornithine- ¹⁵N₂ (hydrochloride) is the ¹⁵N-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W017018S3

*L-Ornithine-d2 hydrochloride*
L-Ornithine-d₂ (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-N0391S2

L-Citrulline-d6
L-Citrulline-d₆ is the deuterium labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

HY-W017018S1

*L-Ornithine-1,2-13C2 hydrochloride*
L-Ornithine-1,2- ¹³C₂ (hydrochloride) is the ¹³C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.

HY-W010589S1

H-Abu-OH-d2
H-Abu-OH-d₂ is the deuterium labeled H-Abu-OH. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.

HY-W710927

L-2-Aminobutyric acid-d5
L-2-Aminobutyric acid-d₅ is the deuterium labeled H-Abu-OH (HY-W010589). H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.

HY-N0391S6

L-Citrulline-d2
L-Citrulline-d₂ is the deuterium labeled L-Citrulline (HY-N0391). L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.

Host:	Rabbit (2)
Reactivity:	Human (2)
Application:	IHC-P (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81485

	Ornithine Carbamoyltransferase/OTC Antibody (YA1230) OTCase; Ornithine carbamoyltransferase; mitochondrial; OCTD	IHC-P	Human
	Ornithine Carbamoyltransferase/OTC Antibody (YA1230) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Ornithine Carbamoyltransferase/OTC.

HY-P81485A

	Ornithine Carbamoyltransferase/OTC Antibody (YA1230)(PBS only) OTCase; Ornithine carbamoyltransferase; mitochondrial; OCTD	IHC-P	Human
	Ornithine Carbamoyltransferase/OTC Antibody (YA1230) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Ornithine Carbamoyltransferase/OTC.

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Cat. No.	Product Name		Classification

HY-151748

N3-L-Orn(Fmoc)-OH		Azide
N3-L-Orn(Fmoc)-OH is a Fmoc-protected ornithine derivative, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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