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P2Y receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P2Y Receptor (139) 5-HT Receptor (1) Akt (1) Apoptosis (4) Arrestin (2) Autophagy (1) Biochemical Assay Reagents (3) Calcium Channel (4) Caspase (2) CD73 (2) DNA/RNA Synthesis (7) Drug Intermediate (1) Drug Metabolite (6) Endogenous Metabolite (22) ERK (2) Estrogen Receptor/ERR (1) Eukaryotic Initiation Factor (eIF) (3) Ferroptosis (1) FXR (1) G protein-coupled Bile Acid Receptor 1 (1) Glutathione Reductase (GR) (1) Glycosyltransferase (1) Interleukin Related (2) Isotope-Labeled Compounds (14) Keap1-Nrf2 (1) MEK (1) mTOR (1) Na+/Ca2+ Exchanger (1) NF-κB (2) NOD-like Receptor (NLR) (1) NTPDase (1) Orphan GPCR (2) P2X Receptor (6) p38 MAPK (3) PI3K (1) PKA (1) Raf (1) Reference Standards (10) Transmembrane Glycoprotein (3)
By Research Areas:	Cancer (26) Cardiovascular Disease (76) Infection (1) Inflammation/Immunology (47) Metabolic Disease (22) Neurological Disease (23)
Oligonucleotides:	Nucleotide Analogs (5) Adenine Nucleotide (3)

158

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: P2Y Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10064

Ticagrelor 10+ Cited Publications AZD6140; AR-C 126532XX	P2Y Receptor	Cardiovascular Disease Cancer
Ticagrelor (AZD6140) is a reversible oral *P2Y12* receptor antagonist for the treatment of platelet aggregation.

HY-15283

Clopidogrel Maximum Cited Publications 30 Publications Verification Clopidogrelum	P2Y Receptor	Cardiovascular Disease Cancer
Clopidogrel is an orally active platelet inhibitor that targets *P2Y12* receptor. Clopidogrel is used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.

HY-W013093

Uridine triphosphate trisodium salt 4 Publications Verification UTP trisodium salt; Uridine 5'-triphosphate trisodium salt	Endogenous Metabolite P2Y Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound **P2Y2 receptors** .

HY-W010832

Uridine-5'-diphosphate disodium salt 2 Publications Verification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uridine-5'-diphosphate disodium salt is a potent, selective *P2Y₆* receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52 for human P2Y₆ receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-13104

MRS 2578 10+ Cited Publications	P2Y Receptor Apoptosis	Cardiovascular Disease
MRS 2578 is a selective and potent **P2Y6 receptor antagonist with IC₅₀*s of 37 nM (human) and 98 nM (rat). MRS 2578 exhibits insignificant activity at P2Y1, P2Y2, P2Y4, and P2Y11 receptors* .

HY-101044

PPADS tetrasodium 5+ Cited Publications	P2X Receptor Na+/Ca2+ Exchanger	Neurological Disease
PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC₅₀s ranging from 1 to 2.6 μM. PPADS tetrasodiuma blocks native P2Y2-like (IC₅₀~0.9 mM) and recombinant P2Y4 (IC₅₀~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca ²⁺ exchanger in guinea pig airway smooth muscle .

HY-110322A

PPTN 4 Publications Verification	P2Y Receptor	Inflammation/Immunology
PPTN, a chemical probe, is a potent, high-affinity, competitive and highly selective **P2Y14 receptor antagonist with a K_B** value of 434 pM. PPTN exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and immune activity .

HY-110322

PPTN hydrochloride 4 Publications Verification	P2Y Receptor	Inflammation/Immunology
PPTN hydrochloride is a potent, high-affinity, competitive and highly selective **P2Y14 receptor antagonist with a K_B** value of 434 pM. PPTN hydrochloride exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and anti-immune activity .

HY-13831

BPTU 1 Publications Verification BMS-646786	P2Y Receptor	Neurological Disease Cancer
BPTU (BMS-646786) is a non-nucleotide *P2Y₁* receptor allosteric antagonist with antithrombotic activity. BPTU is able to block the P2Y1 receptor located at the neuromuscular junction of the gastrointestinal tract .

HY-108660

PSB-0739 1 Publications Verification	P2Y Receptor	Cardiovascular Disease
PSB-0739 is a high-affinity potent, competitive, nonselective platelet **P2Y₁₂ receptor** antagonist with a K_i values of 24.9 nM. The P2Y₁₂ receptor plays a crucial role in platelet aggregation. Antithrombotic effect .

HY-134353B

ADP-β-S trilithium Adenosine 5'-β-thiodiphosphate trilithium	P2Y Receptor NF-κB Interleukin Related Caspase	Neurological Disease Inflammation/Immunology Cancer
ADP-β-S (Adenosine 5'-(β-thiodiphosphate)) trilithium is a non-hydrolyzable ADP analog and a *P2Y12* receptor agonist. ADP-β-S trilithium activates the *P2Y12* receptor in microglia, thereby triggering downstream inflammatory signaling pathways. ADP-β-S trilithium activates *P2Y* purinergic receptors in rat pancreatic β cells and enhances glucose-induced insulin secretion. ADP-β-S trilithium can be used in the research of diseases such as inflammation and diabetes .

HY-B0606

Diquafosol tetrasodium 5 Publications Verification INS365	P2Y Receptor	Inflammation/Immunology
Diquafosol tetrasodium is a *P2Y2* receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease.

HY-108648

2-MeS-ADP trisodium 2-Methylthioadenosine diphosphate trisodium; 2-Methylthio-ADP trisodium	P2Y Receptor	Neurological Disease
2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC₅₀s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC₅₀s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. 2-Methylthioadenosine diphosphate trisodium induces platelet aggregation and shape change, and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1 .

HY-15284

Prasugrel 1 Publications Verification PCR 4099	P2Y Receptor	Cardiovascular Disease
Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent *P2Y12* receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-15284A

Prasugrel hydrochloride 1 Publications Verification PCR 4099 hydrochloride	P2Y Receptor	Cardiovascular Disease
Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent *P2Y12* receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-108648A

2-MeSADP 2-Methylthioadenosine diphosphate; 2-Methylthio-ADP	P2Y Receptor	Neurological Disease
2-MeSADP is a *P2Y* receptor agonist, with an EC₅₀ of 5 nM for human *P2Y12, EC₅₀* values of 19 nM and 13 nM for human *P2Y13, and an EC₅₀* of 6.2 nM for mouse *P2Y13. It shows slightly higher selectivity for P2Y12* over human *P2Y13*. 2-MeSADP triggers increases in intracellular calcium levels, Gi-mediated cAMP inhibition, adenylate cyclase inhibition and downstream signal transduction. 2-MeSADP can be used in research related to glaucoma .

HY-113044R

Uridine 5′-diphosphoglucose (Standard) UDP-D-Glucose (Standard)	Reference Standards Endogenous Metabolite P2Y Receptor	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Uridine 5′-diphosphoglucose (Standard) (UDP-D-Glucose (Standard)) is the analytical standard of Uridine 5′-diphosphoglucose (HY-113044). This product is intended for research and analytical applications. Uridine 5’-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory *P2Y14* receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.

HY-108662

PIT 2,2'-Pyridylisatogen tosylate	P2Y Receptor	Inflammation/Immunology Cancer
PIT (2,2'-Pyridylisatogen tosylate) is a selective and non-competitive antagonist of **P2Y1 receptor with an IC₅₀** value of 0.14 μM for human P2Y1 receptor. PIT antagonizes P2Y1 receptor signaling without affecting nucleotide binding. PIT is an irreversible antagonist of responses to ATP at metabotropic purinoceptors (of the P2Y family) in some smooth muscles. PIT can be used for the research of chronic bronchitis and asthma .

HY-W010820

Uridine 5'-diphosphate sodium salt 2 Publications Verification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uridine 5'-diphosphate sodium salt is a potent, selective *P2Y₆* receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52) and a potent *P2Y₁₄* antagonist (pEC₅₀=7.28). Uridine 5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-129576

PSB-16133 sodium	P2Y Receptor	Inflammation/Immunology
PSB-16133 (sodium) is a tool compound specifically designed to block P2Y receptor subtypes .

HY-113359

Uridine 5'-diphosphate UDP	P2Y Receptor Endogenous Metabolite	Metabolic Disease Inflammation/Immunology
Uridine 5'-diphosphate (UDP) is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-108658

MRS2500 tetraammonium	P2Y Receptor	Cardiovascular Disease
MRS2500 tetraammonium is a potent, selective and stable antagonist of the *P2Y1* receptor (K_i=0.78 nM for recombinant human P2Y1 receptor). MRS2500 tetraammonium inhibits the ADP-induced aggregation of human platelets with an IC₅₀ value of 0.95 nM. Antithrombotic activity .

HY-109122

Selatogrel ACT-246475	P2Y Receptor	Cardiovascular Disease
Selatogrel (ACT-246475) is a reversible and selective *P2Y₁₂* receptor antagonist which inhibits platelet aggregation with an IC₅₀ of 8 nM. Selatogrel exhibits antithrombotic efficacy .

HY-W250153

Adenosine 3'-phosphate 5'-phosphosulfate lithium	P2Y Receptor	Cardiovascular Disease
Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective *P2Y1* antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca ²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-134807

Indophagolin	P2X Receptor 5-HT Receptor Autophagy	Cancer
Indophagolin is a potent, indoline-containing autophagy inhibitor (IC₅₀=140 nM). Indophagolin antagonizes the purinergic receptor P2X₄ as well as P2X₁ and P2X₃ with IC₅₀s of 2.71, 2.40 and 3.49 μM, respectively. Indophagolin also antagonizes the G_q-protein-coupled P2Y₄, P2Y₆, and P2Y₁₁ receptors (IC₅₀s =3.4~15.4 μM). Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT₆ (IC₅₀=1.0 μM) and a moderate effect on receptors 5-HT_1B, 5-HT_2B, 5-HT_4e, and 5-HT₇ .

HY-15876

Clopidogrel thiolactone	Drug Metabolite P2Y Receptor	Cardiovascular Disease
Clopidogrel thiolactone is an important intermediate in the metabolism of Clopidogrel (HY-15283). Clopidogrel thiolactone has antiplatelet aggregatione effects. Clopidogrel is a **P2Y12 receptor** inhibitor that exerts antiplatelet effects .

HY-108659

NF340	P2Y Receptor	Inflammation/Immunology
NF340 is a *P2Y11* receptor inhibitor with a pIC₅₀ of 7.3-7.7 against human *P2Y11* receptor, and it exhibits high selectivity over other P2Y family receptors. NF340 binds to the ATP-binding amino acid residues of the *P2Y11* receptor to inhibit its activity, block nociceptive activity, and reduce spinal dorsal horn *P2Y11* receptor upregulation induced by spinal cord injury. NF340 attenuates the NFκB signaling pathway activated by IL-1β by decreasing IκBα phosphorylation, nuclear p65 accumulation and NFκB promoter activity. NF340 inhibits IL-1β-induced pro-inflammatory cytokine expression, reduces intracellular ROS and 4-HNE levels, and suppresses IL-1β-induced matrix metalloproteinase expression in primary fibroblast-like synoviocytes. NF340 inhibits ATP-induced elevation of intracellular calcium ²⁺ concentration and cell migration in human hepatocellular carcinoma cells. NF340 is applicable to the research of neuropathic pain, myocardial ischemia/reperfusion injury, inflammatory pain, rheumatoid arthritis and hepatocellular carcinoma .

HY-113044

Uridine 5′-diphosphoglucose UDP-D-Glucose	Endogenous Metabolite P2Y Receptor	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Uridine 5’-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory *P2Y14* receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .

HY-101308A

MRS2179 tetrasodium hydrate 2 Publications Verification	P2Y Receptor	Cardiovascular Disease
MRS2179 tetrasodium hydrate is a competitive *P2Y1* receptor antagonist, with a K_b of 102 nM and a pA₂ of 6.99 for turkey P2Y1 receptor. MRS2179 tetrasodium hydrate is selective for P2Y1 over P2X1 (IC₅₀=1.15 µM), P2X3 (12.9 µM), P2X2, P2X4, P2Y2, P2Y4, and P2Y6 receptors . MRS2179 tetrasodium hydrate inhibits platelet aggregation .

HY-108656

MRS2365	P2Y Receptor Arrestin	Cardiovascular Disease
MRS2365 is a potent and selective **P2Y1 receptor (EC₅₀=0.4 nM) /[ ³⁵S]GTPγS binding/β-arrestin 2 recruitment agonist with an EC₅₀** of 0.4 nM. MRS2365 relieves mechanical allodynia and increases mechanical sensitivity. MRS2365 shows little agonist or antagonist activity at the P2Y12 or P2Y13 receptors .

HY-164090

Adenosine 3'-phosphate 5'-phosphosulfate	P2Y Receptor	Cardiovascular Disease
Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on *P2Y2, P2Y4, or P2Y6* receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca ²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-137955

MRS 2211 sodium hydrate	P2Y Receptor	Cardiovascular Disease Others Neurological Disease
MRS 2211 sodium hydrate is a competitive *P2Y13* receptor antagonist (pIC₅₀= 5.97). MRS 2211 sodium hydrate is highly selective to the *P2Y13* receptor, showing more than 20-fold selectivity compared to the P2Y1 and P2Y12 receptors. MRS 2211 sodium hydrate can be used to further investigate the role of the *P2Y13* receptor in different physiological and pathological processes, such as its function in blood cells, the nervous system and the immune system .

HY-168098

P2Y6R antagonist 1	P2Y Receptor	Inflammation/Immunology
P2Y6R antagonist 1 (compound 5ab) is a selective, orally active P2Y6R antagonist with an IC₅₀ value of 19.6 nM. P2Y6R antagonist 1 has anti-inflammatory activity .

HY-161727

P2Y14R antagonist 1	P2Y Receptor NOD-like Receptor (NLR)	Inflammation/Immunology
P2Y14R antagonist 1 (compound I-17) is a selective *P2Y14R* antagonist with an IC₅₀ of 0.6 nM. It exhibits potent *P2Y14R* antagonistic activity, both in vitro and in vivo efficacy, and favorable pharmacokinetic profiles. P2Y14R antagonist 1 reduces the release of inflammatory factors and cell pyroptosis through the NOD-like receptor family pyrin domain-containing 3 (NLRP3)/gasdermin D (GSDMD) signaling pathway. P2Y14R antagonist 1 holds promise for research in the field of acute gouty arthritis .

HY-123669

R-138727	P2Y Receptor Drug Metabolite	Cardiovascular Disease
R-138727, the major active metabolite of Prasugrel (HY-15284), is a highly potent and selective irreversible antagonist of the P2Y12 receptor, with an IC₅₀ of 2.5 μM. R-138727 covalently binds to the P2Y12 receptor on the platelet surface, blocking adenosine diphosphate-mediated platelet activation and aggregation. R-138727 can be used to study stroke, cerebral infarction and neurological deficits.

HY-108649A

MRS2768 tetrasodium salt	P2Y Receptor	Cardiovascular Disease
MRS2768 tetrasodium salt is a moderately potent and selective **P2Y2 receptor** agonist. MRS2768 tetrasodium salt has a protective effect on cardiomyocytes from ischemic damage in vivo and in vitro .

HY-110089

mrs 4062 TEA	P2Y Receptor	Inflammation/Immunology
mrs 4062 (TEA) is a selective *P2Y₄* receptor agonist with an EC₅₀ of 23 nM. mrs 4062 (TEA) has EC₅₀s of 640 nM and 740 nM for P2Y₂ and P2Y₆, respectively .

HY-113359AS2

Uridine 5'-diphosphate-13C9,15N2 dilithium UDP-13C9,15N2 dilithium	Isotope-Labeled Compounds Endogenous Metabolite P2Y Receptor	Others
Uridine 5'-diphosphate- ¹³C₉, ¹⁵N₂ dilithium is ¹³C and ¹⁵N-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-115273

MRS-2179	P2Y Receptor	Others
MRS-2179 is a selective and competitive antagonist for **P2Y1 receptor**, with K_B of 0.177 μM .

HY-10064S

Ticagrelor-d7	Isotope-Labeled Compounds P2Y Receptor	Cardiovascular Disease Cancer
Ticagrelor-d₇ is the deuterium labeled Ticagrelor. Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation .

HY-77734

AR-C133913XX	Drug Metabolite	Cardiovascular Disease
AR-C124910XX is a metabolite of Ticagrelor (HY-10064 ). Ticagrelor is a reversible oral *P2Y12* receptor antagonist, and can be used for study of platelet aggregation .

HY-133781

cis-Clopidogrel-MP derivative Clopidogrel-MP-AM	Drug Metabolite	Others
cis-Clopidogrel-MP derivative (Clopidogrel-MP-AM) is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite . Clopidogrel is an orally active platelet inhibitor that targets P2Y12 receptor .

HY-137418

2-MeS-ATP 2-Methylthio-ATP	P2Y Receptor	Others Inflammation/Immunology
2-MeS-ATP (2-Methylthio-ATP) is an analog of adenosine nucleotides and acts as a **P2Y purinergic receptor** agonist specific for adenosine nucleotide activation. 2-MeS-ATP is also able to inhibit the release of toxic mediators from macrophages stimulated by endotoxin (LPS). 2-MeS-ATP can be used in the study of endotoxin shock and inflammatory diseases .

HY-101308

MRS2179 tetrasodium	P2Y Receptor	Cardiovascular Disease
MRS2179 tetrasodium is a competitive *P2Y1* receptor antagonist, with a K_b of 102 nM and a pA₂ of 6.99 for turkey P2Y1 receptor. MRS2179 tetrasodium is selective for P2Y1 over P2X1 (IC₅₀=1.15 µM), P2X3 (12.9 µM), P2X2, P2X4, P2Y2, P2Y4, and P2Y6 receptors . MRS2179 tetrasodium inhibits platelet aggregation .

HY-179133

HDB-1	P2Y Receptor PKA Raf MEK ERK	Inflammation/Immunology
HDB-1 is a selective inhibitor of the P2Y14 receptor (P2Y14R) with an IC₅₀ of 26 pM. HDB-1 shows no significant inhibition on P2Y1R, P2Y2R, P2Y4R, P2Y6R, and P2Y12R. HDB-1 blocks the activation of hepatic stellate cells (HSC) by inhibiting the PKA/Raf1/MEK/ERK signaling pathway mediated by P2Y14R, thereby alleviating the core pathological process of liver fibrosis. HDB-1 can be used for the study of liver fibrosis .

HY-108671

NF110	P2X Receptor	Neurological Disease
NF110 is a P2X₃ receptor antagonist (K_i = 36 nM) and inactive toward P2Y receptors stably expressed (IC₅₀s > 10 M). NF110 blocks alphabeta-methylene-ATP-induced currents (IC₅₀ = 527 nM) in rat dorsal root ganglia neurons .

HY-134353A

ADP-β-S trisodium Adenosine 5'-(β-thiodiphosphate) trisodium	Interleukin Related P2Y Receptor NF-κB Caspase	Neurological Disease Inflammation/Immunology Cancer
ADP-β-S (Adenosine 5'-(β-thiodiphosphate)) trilithium is a non-hydrolyzable ADP analog and a *P2Y12* receptor agonist. ADP-β-S trilithium activates the *P2Y12* receptor in microglia, thereby triggering downstream inflammatory signaling pathways. ADP-β-S trilithium activates *P2Y* purinergic receptors in rat pancreatic β cells and enhances glucose-induced insulin secretion. ADP-β-S trilithium can be used in the research of diseases such as inflammation and diabetes .

HY-N9422

Adenosine 3'-phosphate 5'-phosphosulfate triethylamine	P2Y Receptor	Cardiovascular Disease
Adenosine 3'-phosphate 5'-phosphosulfate triethylamine, an adenine nucleotide derivative, is a selective *P2Y1* antagonist with no effect on *P2Y2, P2Y4, or P2Y6* receptors. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca ²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-125313

PSB-1737	Orphan GPCR	Cardiovascular Disease Inflammation/Immunology
PSB-1737 is a human-selective GPR17 agonist with an EC₅₀ for human GPR17 of 270 nM, and its activity on murine GPR17 is relatively weak (EC₅₀ > 10 μM). PSB-1737 shows no significant inhibition at the glycine binding site of NMDA receptors, and has no significant agonistic or antagonistic activity on P2Y receptor subtypes. PSB-1737 can be used in demyelinating diseases (such as multiple sclerosis) or inflammatory-related anemia .

HY-137602

P1,P2-Diuridine-5’-diphosphate Up2U	P2Y Receptor	Others
P1,P2-Diuridine-5’-diphosphate (Up2U) is a symmetrical dinucleoside polyphosphate containing two pyrimidine base moieties. P1,P2-Diuridine-5’-diphosphate is also an activator of purinergic P2Y receptor .

Cat. No.	Product Name	Type

HY-114364

UDP-Galactose disodium 4 Publications Verification	Biochemical Assay Reagents
UDP-Galactose disodium is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose disodium is the natural agonist of the **P2Y₁₄ receptor coupled to G_i proteins in the immune system (IC₅₀**= 0.67 μM, hP2Y₁₄). UDP-Galactose disodium can be used to study cell signal transduction and substance metabolism .

HY-W250153

Adenosine 3'-phosphate 5'-phosphosulfate lithium

Biochemical Assay Reagents

Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca ²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-107372H

UTP trisodium salt, 100 mM Solution, PCR Grade

Uridine 5'-triphosphate trisodium salt, 100 mM Solution, PCR Grade

Biochemical Assay Reagents

UTP (Uridine 5'-triphosphate) trisodium salt, 100 mM Solution, PCR Grade is a solution prepared from uridine triphosphate at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, suitable for molecular biology research. Uridine triphosphate (HY-107372) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors .

HY-W250153A

Adenosine 3'-phosphate 5'-phosphosulfate lithium, hydrate

Biochemical Assay Reagents

Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca ²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7032

Uridine 5′-diphosphoglucose disodium Maximum Cited Publications 8 Publications Verification UDP-D-Glucose disodium	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite P2Y Receptor
Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory *P2Y14* receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.

HY-W013093

Uridine triphosphate trisodium salt 4 Publications Verification UTP trisodium salt; Uridine 5'-triphosphate trisodium salt	Cardiovascular Disease Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite P2Y Receptor
Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound **P2Y2 receptors** .

HY-W010832

Uridine-5'-diphosphate disodium salt 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine-5'-diphosphate disodium salt is a potent, selective *P2Y₆* receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52 for human P2Y₆ receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-114364

UDP-Galactose disodium 4 Publications Verification	Structural Classification Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite P2Y Receptor
UDP-Galactose disodium is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose disodium is the natural agonist of the **P2Y₁₄ receptor coupled to G_i proteins in the immune system (IC₅₀**= 0.67 μM, hP2Y₁₄). UDP-Galactose disodium can be used to study cell signal transduction and substance metabolism .

HY-107372

Uridine triphosphate UTP; Uridine 5'-triphosphate	Cardiovascular Disease Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite DNA/RNA Synthesis P2Y Receptor
Uridine triphosphate (UTP; Uridine 5'-triphosphate) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound **P2Y2 receptors** .

HY-113044R

Uridine 5′-diphosphoglucose (Standard) UDP-D-Glucose (Standard)	Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite P2Y Receptor
Uridine 5′-diphosphoglucose (Standard) (UDP-D-Glucose (Standard)) is the analytical standard of Uridine 5′-diphosphoglucose (HY-113044). This product is intended for research and analytical applications. Uridine 5’-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory *P2Y14* receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue.

HY-W010820

Uridine 5'-diphosphate sodium salt 2 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology Source Classification	P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine 5'-diphosphate sodium salt is a potent, selective *P2Y₆* receptor native agonist (EC₅₀=300 nM; pEC₅₀=6.52) and a potent *P2Y₁₄* antagonist (pEC₅₀=7.28). Uridine 5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

HY-113359

Uridine 5'-diphosphate UDP	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	P2Y Receptor Endogenous Metabolite
Uridine 5'-diphosphate (UDP) is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-150524

UDP-Galactose	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite P2Y Receptor
UDP-Galactose is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose is the natural agonist of the **P2Y₁₄ receptor coupled to G_i proteins in the immune system (IC₅₀**= 0.67 μM, hP2Y₁₄). UDP-Galactose can be used to study cell signal transduction and substance metabolism .

HY-N0910

Notoginsenoside Ft1 1 Publications Verification	Triterpenes Structural Classification Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Araliaceae Source Classification	PI3K mTOR Akt Apoptosis p38 MAPK ERK Transmembrane Glycoprotein Glutathione Reductase (GR) Estrogen Receptor/ERR Calcium Channel Ferroptosis G protein-coupled Bile Acid Receptor 1 FXR
Notoginsenoside Ft1 is an orally active bioactive saponin. Notoginsenoside Ft1 inhibits the PI3K/AKT/mTOR signaling pathway, activates the p38 MAPK and ERK1/2 signaling pathways, and increases the proportion of CD8 ⁺ T cells, thereby inducing apoptosis and lysosomal cell death in various cancer cells, and promoting angiogenesis. Notoginsenoside Ft1 causes vasodilation by activating glucocorticoid receptors (GR) and estrogen receptor beta (ERβ) in endothelial cells. Notoginsenoside Ft1 increases intracellular Ca ²⁺ accumulation, reduces cAMP levels by activating a signaling network mediated through *P2Y₁₂* receptors, and promotes platelet aggregation, thereby exerting a procoagulant effect. Notoginsenoside Ft1 inhibits ferroptosis (ferroptosis) in renal tubular epithelial cells by activating the TGR5 receptor, thereby demonstrating a renal protective effect. Notoginsenoside Ft1 acts as a TGR5 agonist and an FXR antagonist to combat obesity and insulin resistance .

HY-113044

Uridine 5′-diphosphoglucose UDP-D-Glucose	Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite P2Y Receptor
Uridine 5’-diphosphoglucose (UDP-glucose), secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory *P2Y14* receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .

HY-148596

UDP-GlcNAc UDP-N-Acetyl-D-glucosamine; Uridine diphospho-N-acetylglucosamine; UDP-N-acetylglucosamine	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite P2Y Receptor Drug Intermediate Glycosyltransferase
UDP-GlcNAc (UDP-N-Acetyl-D-glucosamine) is an important component and precursor of bacterial peptidoglycan. UDP-GlcNAc is a nucleotide sugar used by Glycosyltransferases to synthesize glycoproteins, glycosaminoglycans, glycolipids, and glycoRNA. UDP-GlcNAc also serves as the donor substrate for forming O-GlcNAc, a dynamic intracellular protein modification involved in diverse signaling and disease processes. UDP-GlcNAc is the sugar nucleotide donor for the synthesis of O-GlcNAc modified proteins. UDP-GlcNAc also acts as a full agonist of the *P2Y₁₄* receptor and inhibits the formation of cAMP. UDP-GlcNAc can be used in studies related to bacterial infections .

HY-N7740

Adenosine 2',5'-diphosphate sodium	Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	P2Y Receptor Endogenous Metabolite
Adenosine 2',5'-diphosphate sodium is a competitive *P2Y1* antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors .

HY-W013093R

Uridine triphosphate trisodium salt (Standard) UTP trisodium salt (Standard); Uridine 5'-triphosphate trisodium salt (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite P2Y Receptor
Uridine triphosphate (trisodium salt) (Standard) is the analytical standard of Uridine triphosphate (trisodium salt). This product is intended for research and analytical applications. Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors .

HY-W010832R

Uridine-5'-diphosphate disodium salt (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards P2Y Receptor DNA/RNA Synthesis Endogenous Metabolite
Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52 for human P2Y6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis .

Species:	Human (4)
Tag:	His (4) Flag (2)
Source:	E. coli Cell-free (2) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701629

	P2Y1 Protein, Human (sf9, FLAG) P2RY1; P2Y purinoceptor 1; P2Y1; ADP receptor; Purinergic receptor	Human	Sf9 insect cells
	The P2Y1 protein acts as a receptor for extracellular adenine nucleotides, specifically ADP. In platelets, ADP binding activates phospholipase C, leading to intracellular calcium mobilization, platelet shape changes, and aggregation. P2Y1 Protein, Human (sf9, FLAG) is the recombinant human-derived P2Y1 protein, expressed by Sf9 insect cells, with C-10*His and N-Flag labeled tag.

HY-P701630

	P2Y1 Protein, Human (sf9, FLAG, His) P2RY1; P2Y purinoceptor 1; P2Y1; ADP receptor; Purinergic receptor	Human	Sf9 insect cells
	The P2Y1 protein acts as a receptor for extracellular adenine nucleotides, specifically ADP. In platelets, ADP binding activates phospholipase C, leading to intracellular calcium mobilization, platelet shape changes, and aggregation. P2Y1 Protein, Human (sf9, FLAG, His) is the recombinant human-derived P2Y1 protein, expressed by sf9 insect cells , with C-10*His, N-Flag labeled tag.

HY-P705683

	GPR91 Protein, Human (Cell-Free, His) Succinate receptor 1 Curated; Alternative names; G-protein coupled receptor 91; P2Y purinoceptor 1-like; SUCNR1; GPR91	Human	E. coli Cell-free

HY-P705954

	GPR17 Protein, Human (Cell-Free, His) GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12	Human	E. coli Cell-free

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Cat. No.	Product Name	Chemical Structure

HY-113359AS2

Uridine 5'-diphosphate-13C9,15N2 dilithium
Uridine 5'-diphosphate- ¹³C₉, ¹⁵N₂ dilithium is ¹³C and ¹⁵N-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-10064S

Ticagrelor-d7
Ticagrelor-d₇ is the deuterium labeled Ticagrelor. Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation .

HY-15284S2

Prasugrel-d4
Prasugrel-d₄ is the deuterium labeled Prasugrel . Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-114364S

UDP-α-D-Galactose-13C disodium

UDP-α-D-Galactose- ¹³C disodium is the ¹³C labeled UDP-α-D-Galactose disodium. UDP-Galactose disodium is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose disodium is the natural agonist of the P2Y₁₄ receptor coupled to G_i proteins in the immune system (IC₅₀= 0.67 μM, hP2Y₁₄). UDP-Galactose disodium can be used to study cell signal transduction and substance metabolism .

HY-N7032S1

Uridine 5′-diphosphoglucose-13C6 disodium

Uridine 5′-diphosphoglucose- ¹³C₆ (UDP-D-Glucose- ¹³C₆) disodium is the ¹³C labeled Uridine 5′-diphosphoglucose disodium (HY-N7032) . Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .

HY-N7032S

Uridine 5′-diphosphoglucose-13C disodium

Uridine 5′-diphosphoglucose- ¹³C (UDP-D-Glucose- ¹³C) disodium is the ¹³C labeled Uridine 5′-diphosphoglucose disodium (HY-N7032) . Uridine 5’-diphosphoglucose (UDP-glucose) disodium, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .

HY-113359AS3

Uridine 5'-diphosphate-15N2 dilithium
Uridine 5'-diphosphate- ¹⁵N₂ dilithium is ¹⁵N labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor.

HY-113359AS

Uridine 5'-diphosphate-d12 dilithium
Uridine 5'-diphosphate-d₁₂ (UDP-d12) dilithium is the deuterium labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-113359AS1

Uridine 5'-diphosphate-13C9 dilithium
Uridine 5'-diphosphate- ¹³C₉ (UDP-13C9 ) dilithium is ¹³C-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a *P2Y₆* receptor agonist with an EC₅₀ of 0.013 μM for human P2Y₆ receptor .

HY-10064S1

Ticagrelor-d4
Ticagrelor-d₄ (AZD6140-d₄) is deuterium labeled Ticagrelor. Ticagrelor (AZD6140) is a reversible oral *P2Y12* receptor antagonist for the treatment of platelet aggregation.

HY-15284S1

Prasugrel-d3
Prasugrel-d₃ is the deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-15284S

Prasugrel-d5
Prasugrel-d₅ is deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and prodrug, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-15284S3

Prasugrel-13C6
Prasugrel-13C6 is a deuterated labeled Prasugrel . Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent *P2Y12* receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-107867S1

(Rac)-Clopidogrel hydrogen-d9 sulfate

(Rac)-Clopidogrel hydrogen-d₉ sulfate is the deuterium labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .

HY-107867S2

Clopidogrel-13C,d3 sulfate

Clopidogrel- ¹³C,d₃ sulfate is the deuterium and ¹³C-labeled (±)-Clopidogrel (bisulfate) (HY-107867). (±)-Clopidogrel bisulfate is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel bisulfate inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel bisulfate reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel bisulfate has anti-inflammatory effects .

HY-15283AS1

(±)-Clopidogrel-d4

(±)-Clopidogrel-d₄ ((±)-Clopidogrelum-d₄) is the deuterium labeled (±)-Clopidogrel (HY-107867). (±)-Clopidogrel is a platelet P2Y12 receptor inhibitor and an adenosine diphosphate (ADP) receptor antagonist. (±)-Clopidogrel inhibits the binding of ADP to its receptors on the membranes of platelet cells, and blocks ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. (±)-Clopidogrel reduces vascular inflammation and angiotensin II induced-abdominal aortic aneurysm progression. (±)-Clopidogrel has anti-inflammatory effects .

Host:	Rat (1) Rabbit (4)
Reactivity:	Human (4) Mouse (1) Rat (3)
Application:	IHC-P (3) ICC/IF (2) IP (2) IHC-F (3) WB (4)
Isotype:	IgG (4) IgG1 (1)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (3) Recombinant (3)
Modification:	Unmodified (3)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81901

	OXGR1 Antibody (YA1646) P2Y15; Alpha-ketoglutarate receptor 1; G-protein coupled receptor 80; G-protein coupled receptor 99; P2Y purinoceptor 15	WB	Human, Rat
	OXGR1 Antibody (YA1646) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to OXGR1.

HY-P81901A

	OXGR1 Antibody (YA1646)(PBS only) P2Y15; Alpha-ketoglutarate receptor 1; G-protein coupled receptor 80; G-protein coupled receptor 99; P2Y purinoceptor 15	WB	Human, Rat
	OXGR1 Antibody (YA1646) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to OXGR1.

HY-P87002

	P2Y12 Antibody (YA6695) 1 Publications Verification ADP glucose receptor antibody; ADP-glucose receptor antibody; ADPG R antibody; ADPG-R antibody; ADPGR antibody; BDPLT8 antibody; G protein coupled receptor SP1999 antibody; Gi coupled ADP receptor HORK 3 antibody; Gi coupled ADP receptor HORK3 antibody; HORK 3 antibody; ADP glucose receptor antibody; ADP-glucose receptor antibody; ADPG R antibody; ADPG-R antibody; ADPGR antibody; BDPLT8 antibody; G protein coupled receptor SP1999 antibody; Gi coupled ADP receptor HORK 3 antibody; Gi coupled ADP receptor HORK3 antibody; HORK 3 antibody; HORK3 antibody; P2RY 12 antibody; P2RY12 antibody; P2T(AC) antibody; P2Y 12 antibody; P2Y purinoceptor 12 antibody; P2Y(12)R antibody; P2Y(AC) antibody; P2Y(ADP) antibody; P2Y(cyc) antibody; P2Y12 antibody; P2Y12 platelet ADP receptor antibody; P2Y12_HUMAN antibody; Platelet ADP receptor antibody; Purinergic receptor P2RY12 antibody; Purinergic receptor P2Y G protein coupled 12 antibody; Purinergic receptor P2Y12 antibody; Putative G protein coupled receptor antibody; SP 1999 antibody; SP1999 antibody;	IHC-F, IHC-P	Mouse, Rat
	P2Y12 Antibody (YA6695) is a Rat -derived and non-conjugated IgG1 monoclonal antibody, targeting to P2Y12.

HY-P81946

	P2Y6 Antibody (YA1691) P2ry6; P2Y6; P2Y6 receptor; PP2891	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	P2Y6 Antibody (YA1691) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to P2Y6.

HY-P81946A

	P2Y6 Antibody (YA1691)(PBS only) P2ry6; P2Y6; P2Y6 receptor; PP2891	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	P2Y6 Antibody (YA1691) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to P2Y6.

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HY-W013093

Uridine triphosphate trisodium salt 4 Publications Verification UTP trisodium salt; Uridine 5'-triphosphate trisodium salt		Nucleotide Analogs
Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound **P2Y2 receptors** .

HY-107372

Uridine triphosphate UTP; Uridine 5'-triphosphate		Nucleotide Analogs
Uridine triphosphate (UTP; Uridine 5'-triphosphate) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound **P2Y2 receptors** .

HY-W250153

Adenosine 3'-phosphate 5'-phosphosulfate lithium		Nucleotide Analogs Adenine Nucleotide
Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective *P2Y1* antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca ²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-164090

Adenosine 3'-phosphate 5'-phosphosulfate		Nucleotide Analogs Adenine Nucleotide
Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on *P2Y2, P2Y4, or P2Y6* receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca ²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-W250153A

Adenosine 3'-phosphate 5'-phosphosulfate lithium, hydrate		Nucleotide Analogs Adenine Nucleotide
Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective *P2Y1* antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca ²⁺ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

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