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Picrorhiza scrophulariiflora

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (1) HBV (1) Reference Standards (2) STAT (2)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (6) Metabolic Disease (1) Neurological Disease (1)

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Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0407

Picroside I 6'-Cinnamoylcatalpol	STAT	Inflammation/Immunology
Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .

HY-N0409

Picroside III 1 Publications Verification	Others	Inflammation/Immunology
Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .

HY-N5086

Picroside IV	HBV	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

HY-N0407R

Picroside I (Standard) 6'-Cinnamoylcatalpol (Standard)	Reference Standards STAT	Inflammation/Immunology
Picroside I (Standard) is the analytical standard of Picroside I. This product is intended for research and analytical applications. Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .

HY-N0409R

Picroside III (Standard)	Reference Standards Others	Inflammation/Immunology
Picroside III (Standard) is the analytical standard of Picroside III. This product is intended for research and analytical applications. Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .

HY-N17976

Scrophenoside A	Drug Derivative	Inflammation/Immunology
Scrophenoside A (compound 1) is a phenyl glycoside found in the stems of Picrorhiza scrophulariiflora.Scrophenoside A exhibits anti-asthma activity.Scrophenoside A can be used for the research of asthma .

HY-N18373

6-O-Cinnamoyl-D-glucopyranose	Others	Others
6-O-Cinnamoyl-D-glucopyranose is a natural product. 6-O-Cinnamoyl-D-glucopyranose can be isolated the stems of Picrorhiza scrophulariiflora .

Picroside I 6'-Cinnamoylcatalpol	Iridoids Classification of Application Fields Terpenoids Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields Source Classification	STAT
Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .

Picroside III 1 Publications Verification	Monophenols Iridoids Classification of Application Fields Terpenoids Phenols Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields Source Classification	Others
Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .

Picroside IV	Neurological Disease Classification of Application Fields Metabolic Disease Plants Monophenols Iridoids Terpenoids Phenols Scrophulariaceae Picrorhiza scrophulariiflora Pennell Inflammation/Immunology Disease Research Fields Source Classification	HBV
Picroside IV is an iridoid glycoside found in the underground parts of Picrorhiza scrophulariiflora. Picroside IV is a derivative of Catalpol (HY-N0820) . Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects .

Picroside I (Standard) 6'-Cinnamoylcatalpol (Standard)	Structural Classification Iridoids Terpenoids Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Source Classification	Reference Standards STAT
Picroside I (Standard) is the analytical standard of Picroside I. This product is intended for research and analytical applications. Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .

Picroside III (Standard)	Structural Classification Monophenols Iridoids Terpenoids Phenols Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Source Classification	Reference Standards Others
Picroside III (Standard) is the analytical standard of Picroside III. This product is intended for research and analytical applications. Picroside III is an iridoid glycoside isolated from Picrorhiza scrophulariiflora (PS), a traditional Chinese medicine .

Scrophenoside A	Structural Classification Natural Products Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Source Classification	Drug Derivative
Scrophenoside A (compound 1) is a phenyl glycoside found in the stems of Picrorhiza scrophulariiflora.Scrophenoside A exhibits anti-asthma activity.Scrophenoside A can be used for the research of asthma .

6-O-Cinnamoyl-D-glucopyranose	Structural Classification Natural Products Monophenols Phenols Scrophulariaceae Plants Picrorhiza scrophulariiflora Pennell Source Classification	Others
6-O-Cinnamoyl-D-glucopyranose is a natural product. 6-O-Cinnamoyl-D-glucopyranose can be isolated the stems of Picrorhiza scrophulariiflora .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Picrorhiza scrophulariiflora

Inhibitors & Agonists

NaturalProducts

Natural
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