24 Results for "

Pitavastatin

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Pitavastatin" in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-B0144A
CAS No.: 147511-69-1
Synonyms: NK-104
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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13
13 Publications Verification
Cat. No.: HY-B0144
CAS No.: 147526-32-7
Synonyms: NK-104 hemicalcium; Pitavastatin hemicalcium
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Cat. No.: HY-125643
CAS No.: 141750-63-2
Purity:  99.30%
Pitavastatin lactone is a major metabolite of Pitavastatin (HY-B0144A) in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase .
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Cat. No.: HY-135384
CAS No.: 586966-54-3
Purity:  98.46%
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease

tert-Buthyl Pitavastatin is the  metabolite of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor .
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Cat. No.: HY-B0144BS
Pitavastatin-d4 (sodium) is deuterium labeled Pitavastatin (sodium).
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Cat. No.: HY-135383B
CAS No.: 1159588-21-2
Target:  

Drug Isomer

Research Areas:  

Metabolic Disease

(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin Calcium (HY-B0144) .
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Cat. No.: HY-Z3150
CAS No.: 154057-56-4
Target:  

Drug Intermediate

Research Areas:  

Others

Pitavastatin impurity 1 is an impurity of Pitavastatin (HY-B0144A).
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Cat. No.: HY-B0144B
CAS No.: 574705-92-3
Synonyms: NK-104 sodium
Pitavastatin (NK-104) sodium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin sodium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin sodium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin sodium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Cat. No.: HY-B0144AS1
Synonyms: NK-104-d5 sodium
Pitavastatin-d5 (sodium) is the deuterium labeled Pitavastatin sodium. Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.
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Cat. No.: HY-135383
CAS No.: 254452-92-1
Purity:  99.94%
Research Areas:  

Cardiovascular Disease

(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin Calcium (HY-B0144). Pitavastatin Calcium is a potent HMG-CoA reductase inhibitor that can be used for the study of cardiovascular disease .
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Cat. No.: HY-135383A
CAS No.: 254452-88-5
Research Areas:  

Metabolic Disease

(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin Calcium (HY-B0144). Pitavastatin is a potent HMG-CoA reductase inhibitor .
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Cat. No.: HY-108744
CAS No.: 956116-90-8
Research Areas:  

Cardiovascular Disease

Pitavastatin magnesium is an orally active HMG-CoA Reductase inhibitor. Pitavastatin magnesium lowers total cholesterol and low-density lipoprotein cholesterol in a hyperlipidemic rat model. Pitavastatin magnesium can be used in research on cardiovascular and cerebrovascular diseases such as hyperlipidemia .
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Cat. No.: HY-B0144R
CAS No.: 147526-32-7
Synonyms: NK-104 hemicalcium (Standard); Pitavastatin hemicalcium (Standard)
Pitavastatin (Calcium) (Standard) is the analytical standard of Pitavastatin (Calcium). This product is intended for research and analytical applications. Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Cat. No.: HY-B0144S
Synonyms: NK-104-d4 hemicalcium; Pitavastatin-d4 hemicalcium
Pitavastatin-d4 (hemicalcium) is deuterium labeled Pitavastatin (Calcium). Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity[1][2][3].
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Cat. No.: HY-B0144AS3
Synonyms: NK-104-d4-1 sodium
Pitavastatin-d4-1 (NK-104-d4-1) sodium is the deuterium labeled Pitavastatin sodium (HY-B0144B). Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Cat. No.: HY-Z3150R
CAS No.: 154057-56-4
Target:  

Reference Standards

3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline (Pitavastatin Impurity) (Standard) is the analytical standard of 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline (Pitavastatin Impurity). This product is intended for research and analytical applications.
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Cat. No.: HY-21315
CAS No.: 185105-98-0
Target:  

Drug Intermediate

Research Areas:  

Others

Pitavastatin impurity 12 is an impurity of Pitavastatin (HY-B0144A).
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Cat. No.: HY-125643R
CAS No.: 141750-63-2
Tobramycin (Standard) is the analytical standard of Tobramycin. This product is intended for research and analytical applications. Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms .Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa .
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Cat. No.: HY-W742150
4-Dehydroxy-3-dehydro-pitavastatin lactone-d5 is the deuterium labeled (S,E)-6-(2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-5,6-dihydro-2H-pyran-2-one (Pitavastatin Impurity) (HY-Z3610).
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Cat. No.: HY-180441
CAS No.: 1809100-36-4
Target:  

Drug Metabolite

Research Areas:  

Others

(Rac)-5-Oxo-pitavastatin is a Pitavastatin (HY-B0144A) metabolite .
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