(Z)-Pitavastatin calcium
Based on 1 Customer Validation
(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin Calcium (HY-B0144).
For research use only. We do not sell to patients.
- Purity : 99.63%
- CAS No.: 1159588-21-2
- Formula: C25H24FNO4·1/2Ca
- Molecular Weight:441.54
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Pitavastatin Calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1159588-21-2
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Appearance Solid
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Molecular Weight 441.54
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Formula C25H24FNO4·1/2Ca
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Color White to off-white
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SMILES
FC(C=C1)=CC=C1C2=C(/C=C\[C@@H](O)C[C@@H](O)CC(O)=O)C(C3CC3)=NC4=C2C=CC=C4.[1/2].[Ca]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 9.09 mg/mL (20.59 mM; ultrasonic and adjust pH to 2 with 1 M HCL and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (281 KB)
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SDS (557 KB)
- English - EN (557 KB)
- Français - FR (557 KB)
- Deutsch - DE (557 KB)
- Norwegian - NO (557 KB)
- Español - ES (557 KB)
- Swedish - SV (557 KB)
- Italian - IT (557 KB)
- Korean - KR (557 KB)
- Portuguese - PT (557 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.2648 mL | 11.3240 mL | 22.6480 mL | 56.6200 mL |
| 5 mM | 0.4530 mL | 2.2648 mL | 4.5296 mL | 11.3240 mL | |
| 10 mM | 0.2265 mL | 1.1324 mL | 2.2648 mL | 5.6620 mL | |
| 15 mM | 0.1510 mL | 0.7549 mL | 1.5099 mL | 3.7747 mL | |
| 20 mM | 0.1132 mL | 0.5662 mL | 1.1324 mL | 2.8310 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
(Z)-Pitavastatin calcium Related Classifications
HY-135383B Related Classifications
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