1. Metabolic Enzyme/Protease
  2. HMG-CoA Reductase (HMGCR)
  3. Pitavastatin magnesium

Pitavastatin magnesium is an orally active HMG-CoA Reductase inhibitor. Pitavastatin magnesium lowers total cholesterol and low-density lipoprotein cholesterol in a hyperlipidemic rat model. Pitavastatin magnesium can be used in research on cardiovascular and cerebrovascular diseases such as hyperlipidemia.

For research use only. We do not sell to patients.

Pitavastatin magnesium

Pitavastatin magnesium Chemical Structure

CAS No. : 956116-90-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
5 mg In-stock
10 mg In-stock
25 mg In-stock
50 mg In-stock
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Pitavastatin magnesium is an orally active HMG-CoA Reductase inhibitor. Pitavastatin magnesium lowers total cholesterol and low-density lipoprotein cholesterol in a hyperlipidemic rat model. Pitavastatin magnesium can be used in research on cardiovascular and cerebrovascular diseases such as hyperlipidemia[1][2].

Molecular Weight

862.19

Formula

C50H43F2MgN2O8

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

[O-]C(CC1O[Mg+2](OC(CC2=O)CC(O)/C=C/C3=C(C4=CC=C(F)C=C4)C5=C(C=CC=C5)N=C3C6CC6)([O-]2)OC(C1)/C=C/C7=C(C8=CC=C(F)C=C8)C9=C(C=CC=C9)N=C7C%10CC%10)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (115.98 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1598 mL 5.7992 mL 11.5984 mL
5 mM 0.2320 mL 1.1598 mL 2.3197 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1598 mL 5.7992 mL 11.5984 mL 28.9959 mL
5 mM 0.2320 mL 1.1598 mL 2.3197 mL 5.7992 mL
10 mM 0.1160 mL 0.5799 mL 1.1598 mL 2.8996 mL
15 mM 0.0773 mL 0.3866 mL 0.7732 mL 1.9331 mL
20 mM 0.0580 mL 0.2900 mL 0.5799 mL 1.4498 mL
25 mM 0.0464 mL 0.2320 mL 0.4639 mL 1.1598 mL
30 mM 0.0387 mL 0.1933 mL 0.3866 mL 0.9665 mL
40 mM 0.0290 mL 0.1450 mL 0.2900 mL 0.7249 mL
50 mM 0.0232 mL 0.1160 mL 0.2320 mL 0.5799 mL
60 mM 0.0193 mL 0.0967 mL 0.1933 mL 0.4833 mL
80 mM 0.0145 mL 0.0725 mL 0.1450 mL 0.3624 mL
100 mM 0.0116 mL 0.0580 mL 0.1160 mL 0.2900 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Pitavastatin magnesium
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