Pitavastatin magnesium
Based on 1 Customer Validation
Pitavastatin magnesium is an orally active HMG-CoA Reductase inhibitor. Pitavastatin magnesium lowers total cholesterol and low-density lipoprotein cholesterol in a hyperlipidemic rat model. Pitavastatin magnesium can be used in research on cardiovascular and cerebrovascular diseases such as hyperlipidemia.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.76%
- CAS 番号: 956116-90-8
- 分子式: C50H43F2MgN2O8
- 分子量:862.19
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
化学情報
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CAS 番号 956116-90-8
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性状 Solid
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分子量 862.19
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分子式 C50H43F2MgN2O8
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Color White to light yellow
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SMILES
[O-]C(CC1O[Mg+2](OC(CC2=O)CC(O)/C=C/C3=C(C4=CC=C(F)C=C4)C5=C(C=CC=C5)N=C3C6CC6)([O-]2)OC(C1)/C=C/C7=C(C8=CC=C(F)C=C8)C9=C(C=CC=C9)N=C7C%10CC%10)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (115.98 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Pitavastatin magnesium (Zypitamag) for hyperlipidemia. Med Lett Drugs Ther. 2018 Jun 18;60(1549):106. [Content Brief]
[2]. Abolhasani S, et al. Pitavastatin-induced cholesterol deficiency elevates serum biomarkers associated with statin-related adverse effects in rats. Cardiovasc Endocrinol Metab. 2025 Mar 7;14(2):e00326. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1598 mL | 5.7992 mL | 11.5984 mL | 28.9959 mL |
| 5 mM | 0.2320 mL | 1.1598 mL | 2.3197 mL | 5.7992 mL | |
| 10 mM | 0.1160 mL | 0.5799 mL | 1.1598 mL | 2.8996 mL | |
| 15 mM | 0.0773 mL | 0.3866 mL | 0.7732 mL | 1.9331 mL | |
| 20 mM | 0.0580 mL | 0.2900 mL | 0.5799 mL | 1.4498 mL | |
| 25 mM | 0.0464 mL | 0.2320 mL | 0.4639 mL | 1.1598 mL | |
| 30 mM | 0.0387 mL | 0.1933 mL | 0.3866 mL | 0.9665 mL | |
| 40 mM | 0.0290 mL | 0.1450 mL | 0.2900 mL | 0.7249 mL | |
| 50 mM | 0.0232 mL | 0.1160 mL | 0.2320 mL | 0.5799 mL | |
| 60 mM | 0.0193 mL | 0.0967 mL | 0.1933 mL | 0.4833 mL | |
| 80 mM | 0.0145 mL | 0.0725 mL | 0.1450 mL | 0.3624 mL | |
| 100 mM | 0.0116 mL | 0.0580 mL | 0.1160 mL | 0.2900 mL |