254452-88-5
254452-88-5
Chemical Structure
(3S,5R)-Pitavastatin calcium
- CAS No.: 254452-88-5
- Formula:C25H24FNO4.1/2Ca
- Molecular Weight:440.49
SMILES: [O-]C(C[C@@H](O)C[C@@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C3=C(C=CC=C3)N=C1C4CC4)=O.[1/2].[Ca+2]
Biological Activity: (3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin Calcium (HY-B0144). Pitavastatin is a potent HMG-CoA reductase inhibitor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(3S,5R)-Pitavastatin calcium | 98.53% | (3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin Calcium (HY-B0144). Pitavastatin is a potent HMG-CoA reductase inhibitor. | ||||||||||||||||||||
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References
- [1]. Suzuki, M., et al. First systematic chiral syntheses of two pairs of enantiomers with 3,5-dihydroxyheptenoic acid chain, associated with a potent synthetic statin NK-104. Bioorganic & Medicinal Chemistry Letters. 1999;9(20), 2977–2982. [Content Brief]
- [2]. Ahmad H, et al. Pitavastatin: a new HMG-CoA reductase inhibitor for the treatment of hypercholesterolemia. Cardiol Rev. 2010 Sep-Oct;18(5):264-7.
