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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
55 Results for "
Purine derivative
" in MedChemExpress (MCE) Product Catalog:
Products (55)
55 Results for "Purine derivative" in MCE Product Catalog:
24
24 Publications Verification
Cat. No.: HY-W015213
CAS No.: 6055-72-7
16
Category:
Natural Products Microorganisms Other Diseases Disease markers Endogenous metabolite Disease Research Fields Cancer
Target:
8
8 Cited Publications
Synonyms: Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine
8
8 Cited Publications
Cat. No.: HY-N6666
CAS No.: 24356-66-9
Research Areas:
Vidarabine monohydrate is a Purine nucleoside derivative and Antiviral agent. The triphosphate derivative of Vidarabine monohydrate competitively inhibits DNA polymerase, incorporates into the terminus of elongating DNA molecules, and interferes with the early steps of viral DNA synthesis. Vidarabine monohydrate inhibits the replication of herpes simplex virus, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and vaccinia virus, reduces viral shedding, and accelerates skin healing. Vidarabine monohydrate is metabolized to arabinosyl hypoxanthine, causes minimal impairment of corneal wound healing in rabbit models, and is associated with recurrence of herpes simplex encephalitis. Vidarabine monohydrate can be used in the research of herpetic keratoconjunctivitis, herpes simplex encephalitis, herpetic uveitis, and chronic active hepatitis associated with hepatitis B virus .
3
3
Research Areas:
Guanine hydrochloride is one of the fundamental components of nucleic acids (DNA and RNA). Guanine hydrochloride is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine hydrochloride has the potential to serve as a large-capacity N pool. Guanine hydrochloride has cytotoxic, antinociceptive and neuroprotective effects .
2
2 Cited Publications
Cat. No.: HY-N0091S7
CAS No.: 77910-30-6
Synonyms: Purin-6-ol-15N4; Sarcine-15N4
1
1 Cited Publications
Cat. No.: HY-W011428
CAS No.: 101622-51-9
Olomoucine is an ATP competitive inhibitor of CDKs. Olomoucine is a purine (HY-34431) derivative and inhibits CDC2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E (both IC50=7 μM), CDK/p35 kinase (IC50=3 μM) and ERK1/p44 MAP kinase (IC50=25 μM) . Olomoucine regulates cell cycle and shows anti-melanin tumor activity .
1
1 Cited Publications
Cat. No.: HY-N0091S6
CAS No.: 697807-02-6
Cat. No.: HY-W017163
CAS No.: 552-62-5
Cat. No.: HY-W019033
CAS No.: 4016-63-1
Target:
Research Areas:
8-Bromoguanosine is a purine nucleoside, a brominated derivative of guanosine. 8-Bromoguanosine can reduce the conformational heterogeneity of RNA to enhance its function .
Cat. No.: HY-N0091S5
CAS No.: 2483831-32-7
Cat. No.: HY-W013330
CAS No.: 3608-58-0
Synonyms: Guanosine, 3'-deoxy-
Research Areas:
3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a derivative of Guanosine (HY-N0097). 3′-Deoxyguanosine interacts with human purine nucleoside phosphorylase via hydrogen bonding with residues such as Glu201 and Asn243. 3′-Deoxyguanosine exhibits moderate displacement activity for [ 3H]-guanosine in rat meninges. 3′-Deoxyguanosine is useful for studying the mechanism of guanosine receptors and purine metabolism .
Cat. No.: HY-W007367
CAS No.: 5451-40-1
Target:
Research Areas:
2,6-Dichloropurine is a purine derivative, PDE inhibitor analog, and synthetic intermediate for N 7-glycosylated purine nucleosides, nucleosides and nucleotides. 2,6-Dichloropurine is applicable to cancer-related research .
Cat. No.: HY-N0091S2
CAS No.: 2086337-18-8
Synonyms: Purin-6-ol-13C5; Sarcine-13C5
Cat. No.: HY-W017163S1
CAS No.: 1185878-99-2
Cat. No.: HY-Y1055S
CAS No.: 201489-20-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
