5451-40-1
5451-40-1
Chemical Structure
2,6-Dichloropurine
- CAS No.: 5451-40-1
- Formula:C5H2Cl2N4
- Molecular Weight:189.00
IUPAC Name: 2,6-Dichloropurine
InChIKey: RMFWVOLULURGJI-UHFFFAOYSA-N
SMILES: C2=NC1=C(C(=NC(=N1)Cl)Cl)[NH]2
Biological Activity: 2,6-Dichloropurine is a pharmaceutical intermediate. 2,6-Dichloropurine can be used to synthesize various PDE inhibitors, human A3 adenosine receptor (AR) antagonists, and CDK inhibitors[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2,6-Dichloropurine | 99.81% | 2,6-Dichloropurine is a pharmaceutical intermediate. 2,6-Dichloropurine can be used to synthesize various PDE inhibitors, human A3 adenosine receptor (AR) antagonists, and CDK inhibitors. | ||||||||||||||||||||
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References
- [1]. Kozai S, et al. Synthesis and biological activity of 9-(2, 6-difluorobenzyl)-9H-purines bearing chlorine. Chemical and pharmaceutical bulletin, 1999, 47(4): 574-575.
- [2]. Jeong LS, et al. Discovery of a new nucleoside template for human A3 adenosine receptor ligands: D-4'-thioadenosine derivatives without 4'-hydroxymethyl group as highly potent and selective antagonists. J Med Chem. 2007 Jul 12;50(14):3159-62. [Content Brief]
- [3]. Oumata N, et al. Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1. J Med Chem. 2008 Sep 11;51(17):5229-42. [Content Brief]
Keywords
