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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
RM 137-15
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "RM 137-15" in MCE Product Catalog:
Cat. No.: HY-167002
CAS No.: 3117189-62-2
RM 137-15 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. RM 137-15 can be used in the preparation of liposomes .
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74 Publications Verification
Synonyms: Levarterenol; L-Noradrenaline
74
74 Publications Verification
Synonyms: Levarterenol hydrochloride; L-Noradrenaline hydrochloride
74
74 Publications Verification
Synonyms: Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate
74
74 Publications Verification
Synonyms: Levarterenol tartrate; L-Noradrenaline tartrate
Cat. No.: HY-NP137
Category:
Cat. No.: HY-13715AR
CAS No.: 329-56-6
Synonyms: Levarterenol hydrochloride (Standard); L-Noradrenaline hydrochloride (Standard)
Cat. No.: HY-13715BR
CAS No.: 108341-18-0
Synonyms: Levarterenol (bitartrate monohydrate) (Standard); L-Noradrenaline (bitartrate monohydrate) (Standard)
Category:
Cat. No.: HY-RS13715
Target:
Research Areas:
SPRR2A Human Pre-designed siRNA Set A contains three designed siRNAs for SPRR2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N13715
CAS No.: 16408-77-8
Category:
Alkaloids Other Alkaloids Ranunculaceae Plants Thalictrum isopyroides C. A. Mey. in Ledebour
Target:
Cat. No.: HY-L137
114 compounds
Targeted protein degradation(TPD) is a novel and promising approach to new drug discovery and development. It shows great potential for treating diseases with “undruggable” pathogenic protein targets and for overcoming drug resistance. Molecular glues and PROTACs are both targeted protein degraders that have attracted the most attention.
Molecular glues are small molecular degraders that mainly induce novel interaction between an E3 ligase and a target protein to form a ternary complex, leading to protein ubiquitination and subsequent proteasome degradation. Compared with PROTACs, molecular glues generally possess more favorable drug-like properties, such as lower MW, higher cell permeability, and better oral absorption. Molecular glues are emerging as a promising new therapeutic strategy.
MCE supplies a unique collection of 114 molecular glues which target various proteins. MCE Molecular Glue Compound Library is a useful tool to conduct scientific research and disease mechanism study.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
