1 Result for "

SARS-CoV-2-IN-81

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SARS-CoV-2-IN-81" in MCE Product Catalog:

Cat. No.: HY-161261
Target:  

AAK1 SARS-CoV

Research Areas:  

Infection

SARS-CoV-2-IN-81 (compound 12e) is a potent AAK1 inhibitor with an IC50 value of 9.38 nM. SARS-CoV-2-IN-81 shows anti-viral property against SARS-CoV-2. SARS-CoV-2-IN-81 attenuates AAK1-induced phosphorylation of AP2M1 threonine 156 and disrupts the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection .
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