1 Result for "

ST-056083

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ST-056083" in MCE Product Catalog:

Cat. No.: HY-187641
CAS No.: 299419-24-2
Target:  

Bacterial

Research Areas:  

Infection

ST056083 is a small-molecule inhibitor of the c-di-AMP synthase DisA. The apparent KD of ST056083 binding to DisA is 21 μM. ST056083 reduces c-di-AMP production in Enterococcus faecalis ATCC 29212, and inhibits bacterial growth, biofilm formation, bacterial viability within biofilms, and the synthesis of water-insoluble extracellular polysaccharides. ST056083 is applicable to studies on bacterial c-di-AMP signaling and E. faecalis-associated infections .
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