Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
105 Results for "
Serpin
" in MedChemExpress (MCE) Product Catalog:
Products (105)
105 Results for "Serpin" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P71077
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinE1; Endothelial Plasminogen Activator Inhibitor; Prev. PLANH1; Serpin E1; Prev. PAI1; PAI-1; PAI; Serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade E (Nexi
2
2 Cited Publications
Cat. No.: HY-P7054
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinF1; Testis Tissue Sperm-Binding Protein Li 70n; Prev. PEDF; Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1; EPC-1; Proliferation-Inducing Protein 35; Pigment Epithelium-Derived Factor; Serpin F
2
2 Cited Publications
Cat. No.: HY-P7419
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinA12; Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12; Serpin Family A Member 12; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12; Vaspin; Serpin A12; OL-64; Vis
2
2 Cited Publications
Cat. No.: HY-P70975
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinA5; Acrosomal Serine Protease Inhibitor; Prev. PLANH3; PAI-3; Prev. PCI; Plasminogen Activator Inhibitor III; PROCI; Plasminogen Activator Inhibitor-3; PAI3; Plasminogen Activator Inhibitor 3; Protein C Inhibitor; Serpin A5; Serine (Or Cysteine) Pro
1
Target:
Research Areas:
Serpin B9-IN-1 (BTCA) is an inhibitor that specifically targets Serpin B9 (SB9); SB9 is a natural inhibitor of granzyme B (GrB) , but may promote the metastasis of lung cancer cells into the bone marrow. SB9-overexpressing cancer cells promote proliferation and metastasis in an immune cell-dependent manner by binding to GrB. Inhibition of SB9 by Serpin B9-IN-1 significantly inhibits immunotherapy of lung cancer bone metastases in the caudal artery (CA) mouse model (LCBM) .
1
1 Cited Publications
Cat. No.: HY-P77198
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SerpinB4; Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4; Prev. SCCA2; Serpin B4; Squamous Cell Carcinoma Antigen 2; Protease Inhibitor (Leucine-Serpin); SCCA-2; Squamous Cell Carcinoma Antigen 1; PI11; SCCA2/SCCA1 Fusion Protein; LEUPIN; Leupi
Species:
Source:
1
1 Cited Publications
Cat. No.: HY-P71133
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinE1; Endothelial Plasminogen Activator Inhibitor; Prev. PLANH1; Serpin E1; Prev. PAI1; PAI-1; PAI; Serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade E (Nexi
1
1 Cited Publications
Cat. No.: HY-P73372
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinF1; Testis Tissue Sperm-Binding Protein Li 70n; Prev. PEDF; Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1; EPC-1; Proliferation-Inducing Protein 35; Pigment Epithelium-Derived Factor; Serpin F
1
1 Cited Publications
Cat. No.: HY-P73412
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinA3; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3, Isoform CRA_a; Prev. AACT; Growth-Inhibiting Protein 24; ACT; Growth-Inhibiting Protein 25; Alpha-1-Antichymotrypsin; Alpha-1 Antichymotrypsin; Serpin Peptidase
1
1 Cited Publications
Cat. No.: HY-P70498A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinF1; Testis Tissue Sperm-Binding Protein Li 70n; Prev. PEDF; Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1; EPC-1; Proliferation-Inducing Protein 35; Pigment Epithelium-Derived Factor; Serpin F
1
1 Cited Publications
Cat. No.: HY-P71143
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinA4; Testicular Secretory Protein Li 22; Prev. PI4; Peptidase Inhibitor 4; KST; Kallikrein Inhibitor; Kallistatin; Serpin A4; KLST; PI-4; KAL; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4, Isoform CRA_a; Serine
1
1 Cited Publications
Cat. No.: HY-P72831
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SerpinC1; Signal Peptide Antithrombin Part 1; Prev. AT3; Antithrombin III; ATIII; SerpinC1 Protein; Antithrombin-III; Antithrombin; Serine (Or Cysteine) Proteinase Inhibitor, Clade C (Antithrombin), Member 1; ATIII-R2; Serpin Peptidase Inhibitor, Clade C
1
1 Cited Publications
Cat. No.: HY-P71303
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinB1; Epididymis Secretory Protein Li 27; Prev. ELANH2; Peptidase Inhibitor 2; MNEI; HEL-S-27; PI2; M/NEI; LEI; PI-2; EI; Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1, Isoform CRA_a; Leukocyte Elastase Inhibitor; Protease Inhibitor 2 (Ant
1
1 Cited Publications
Cat. No.: HY-P73526
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinG1; Serine (Or Cysteine) Proteinase Inhibitor, Clade G (C1 Inhibitor), Member 1, (Angioedema, Hereditary); Prev. C1NH; Serine/Cysteine Proteinase Inhibitor Clade G Member 1 Splice Variant 2; Plasma Protease C1 Inhibitor; Serine/Cysteine Proteinase I
Cat. No.: HY-E70194
CAS No.: 137010-42-5
Synonyms: V8 protease; Glu-C
Target:
Research Areas:
Endoproteinase Glu-C (MS grade) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins .
Cat. No.: HY-P991422
Synonyms: DS9231; TS-23; CSL-301
Target:
Research Areas:
Synonyms: PAZ-417
Research Areas:
Aleplastinin (PAZ-417) is an orally active, blood-brain barrier permeable, selective SERPINE1 (PAI-1) inhibitor (IC50=655 nM). Aleplastinin activates the tissue type plasminogen activator (tPA)/fibrinolysis cascade by inhibiting PAI-1, thereby promoting the degradation of amyloid-β (Aβ) oligomers and monomers. Aleplastinin can significantly reduce plasma and brain Aβ levels, improve memory impairment, and reverse cognitive impairment. Aleplastinin can be used for research on Alzheimer's disease .
Target:
Research Areas:
ARN1468 (compound 5) is an orally active and potent SerpinA3n inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 μM .
Cat. No.: HY-P991629
Target:
Research Areas:
Cat. No.: HY-174484
OVA mRNA (5moU) encodes the ovalbumin (OVA) protein, a member of the serpin superfamily and the predominant glycoprotein found in egg whites. It is a commonly used antigen for immunization and biochemical studies and is an established model allergen for airway hyper-responsiveness.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
