2 Results for "

Sp-8-pCPT-cGMPS

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Sp-8-pCPT-cGMPS" in MCE Product Catalog:

Cat. No.: HY-137108
CAS No.: 160385-87-5
Target:  

PKA PKG

Research Areas:  

Neurological Disease

Sp-8-pCPT-cGMPS is a potent cyclic guanosine monophosphate-gated channel agonist and a lipophilic activator of protein kinase G (types I α, I β, and II) and protein kinase A type II with excellent cell membrane permeability and phosphodiesterase stability. Sp-8-pCPT-cGMPS can be used to study the role of cGMP in neural plasticity and synaptic transmission .
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Cat. No.: HY-137633
CAS No.: 172806-21-2
Target:  

PKG

Research Areas:  

Neurological Disease

Sp-8-Br-PET-cGMPS is a membrane-permeable PKG agonist and a membrane-permeable inhibitor of retinal-type cGMP-gated ion channels, as well as an activator of cGMP-dependent protein kinases I α and I β. Sp-8-Br-PET-cGMPS is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, has no metabolic side effects, and is more lipophilic and permeable than Sp-8-pCPT-cGMPS. Sp-8-Br-PET-cGMPS can be used to study the role of cGMP signaling pathways in the nervous system .
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