160385-87-5
Chemical Structure
Sp-8-pCPT-cGMPS
- CAS No.: 160385-87-5
- Formula:C16H15ClN5O6PS2
- Molecular Weight:503.88
IUPAC Name: 2-amino-8-((4-chlorophenyl)thio)-9-((2S,4aR,6R,7R,7aS)-7-hydroxy-2-mercapto-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: PDTDLUUXNODJIA-KYYAAFHFSA-N
SMILES: O[C@@H]1[C@H](O2)[C@@H](CO[P@@]2(S)=O)O[C@H]1N(C(SC3=CC=C(Cl)C=C3)=N4)C5=C4C(NC(N)=N5)=O
Biological Activity: Sp-8-pCPT-cGMPS is a potent cyclic guanosine monophosphate-gated channel agonist and a lipophilic activator of protein kinase G (types I α, I β, and II) and protein kinase A type II with excellent cell membrane permeability and phosphodiesterase stability. Sp-8-pCPT-cGMPS can be used to study the role of cGMP in neural plasticity and synaptic transmission[1].
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Sp-8-pCPT-cGMPS | Sp-8-pCPT-cGMPS is a potent cyclic guanosine monophosphate-gated channel agonist and a lipophilic activator of protein kinase G (types I α, I β, and II) and protein kinase A type II with excellent cell membrane permeability and phosphodiesterase stability. Sp-8-pCPT-cGMPS can be used to study the role of cGMP in neural plasticity and synaptic transmission. | |||||||||||||||||||||
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Keywords
