2 Results for "

Stephania cephalantha Hayata

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Stephania cephalantha Hayata" in MCE Product Catalog:

15
Cepharanthine
Cepharanthine
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15 Cited Publications
Cat. No.: HY-N6972
CAS No.: 481-49-2
Category:  

Infection Alkaloids Stephania cepharantha Hayata Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Menispermaceae Stephania japonica (Thunb.) Miers

Target:  

Autophagy SARS-CoV Cytochrome P450 Apoptosis Parasite

Cepharanthine is a natural product that can be isolated from the plant Stephania cephalantha Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration (IC50) and 90% inhibitory concentration (IC90) values of 1.90 and 4.46 μM . Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model . Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects .
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Cepharanthine (Standard)
Cepharanthine (Standard)
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Cat. No.: HY-N6972R
CAS No.: 481-49-2
Category:  

Alkaloids Stephania cepharantha Hayata Plants Isoquinoline Alkaloids Menispermaceae Stephania japonica (Thunb.) Miers

Target:  

Autophagy Reference Standards SARS-CoV Cytochrome P450 Apoptosis Parasite

Cepharanthine (Standard) is the analytical standard of Cepharanthine. This product is intended for research and analytical applications. Cepharanthine is a natural product that can be isolated from the plant Stephania?cephalantha?Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration (IC50) and 90% inhibitory concentration (IC90) values of 1.90 and 4.46?μM . Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model . Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects .
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