2. Natural Products
  3. Plants
  4. Menispermaceae
  5. Stephania japonica (Thunb.) Miers

Stephania japonica (Thunb.) Miers

Stephania japonica (Thunb.) Miers (3):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N6972
    Cepharanthine 481-49-2 99.91%
    Cepharanthine is a natural product that can be isolated from the plant Stephania cephalantha Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50%) inhibitory concentration (IC50) and 90% inhibitory concentration (IC90) values of 1.90 and 4.46 µM. Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model. Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects.
    Cepharanthine
  • HY-W007656
    Cyclen 294-90-6 99.94%
    Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates.
    Cyclen
  • HY-N11096
    Sinococuline 109351-36-2
    Sinococuline is a potent anti-dengue agent that is effective against all four serotypes of dengue virus (DENV). Sinococuline is also an effective tumor cell growth inhibitor.
    Sinococuline