6 Results for "

TAOK2 kinase

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "TAOK2 kinase" in MCE Product Catalog:

227
227 Cited Publications
Cat. No.: HY-15141
CAS No.: 62996-74-1
Purity:  99.52%
Synonyms: Antibiotic AM-2282; STS; AM-2282
Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer .
loading...
    loading...
Cat. No.: HY-15141R
CAS No.: 62996-74-1
Synonyms: Antibiotic AM-2282 (Standard); STS (Standard); AM-2282 (Standard)
Staurosporine (Standard) is the analytical standard of Staurosporine. This product is intended for research and analytical applications. Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer[1][2][3][4][5].
loading...
    loading...
Cat. No.: HY-181280
Target:  

Ser/Thr Protease

Research Areas:  

Neurological Disease

VU6083859 is a blood-brain barrier-permeable TAOK1 inhibitor with an IC50 of 158 nM. VU6083859 selectively inhibits TAOK1, exhibits only weak or no activity against TAOK2 and TAOK3, and shows high selectivity for a variety of other kinases. VU6083859 is applicable to research related to neurodevelopmental disorders and tauopathies.
loading...
    loading...
Cat. No.: HY-181619
CAS No.: 3114565-22-6
Target:  

MAP3K

TAO Kinase-IN-3 is a potent pan-TAOK (Thousand-And-One Kinase) inhibitor that specifically binds to and inhibits the kinase activities of TAOK1, TAOK2 and TAOK3 with Kd values of <0.17 nM, 0.34 nM, and 0.17 nM, respectively. TAO Kinase-IN-3 can be used to study Alzheimer's disease, primary tauopathies and related syndromes. In addition, TAO Kinase-IN-3 is also widely used in research on the mechanisms of cancer cachexia and the muscle atrophy it induces .
loading...
    loading...
Cat. No.: HY-P701641
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TAOK2; Prostate-Derived Sterile 20-Like kinase 1; TAO kinase 2; kinase From Chicken Homolog C; Serine/Threonine-Protein kinase TAO2; PSK1-BETA; MAP3K17; KIAA0881; HKFC-C; Tao2beta; PSK-1; TAO1; PSK1; TAO2; PSK; Prostate-Derived STE20-Like kinase 1; Thousa
Species:  
Human
Source:  
Sf9 insect cells
loading...
    loading...
Cat. No.: HY-181281
Target:  

Ser/Thr Kinase

Research Areas:  

Neurological Disease Cancer

VU6080195 is a blood-brain barrier-permeable pan-TAOK activator. VU6080195 shows the highest potency against TAOK1 (EC50 = 270 nM), followed by TAOK3 (EC50 = 503 nM) and TAOK2 (EC50 = 1,376 nM). VU6080195 can be used for the research of diseases such as neurodevelopmental disorders, tauopathies and breast cancer .
loading...
    loading...