2. Metabolic Enzyme/Protease
  3. Ser/Thr Kinase
  4. VU6080195

VU6080195 is a blood-brain barrier-permeable pan-TAOK activator. VU6080195 shows the highest potency against TAOK1 (EC50 = 270 nM), followed by TAOK3 (EC50 = 503 nM) and TAOK2 (EC50 = 1,376 nM). VU6080195 can be used for the research of diseases such as neurodevelopmental disorders, tauopathies and breast cancer.

For research use only. We do not sell to patients.

VU6080195

VU6080195 Chemical Structure

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VU6080195 Related Antibodies

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Description

VU6080195 is a blood-brain barrier-permeable pan-TAOK activator. VU6080195 shows the highest potency against TAOK1 (EC50 = 270 nM), followed by TAOK3 (EC50 = 503 nM) and TAOK2 (EC50 = 1,376 nM). VU6080195 can be used for the research of diseases such as neurodevelopmental disorders, tauopathies and breast cancer[1].

Molecular Weight

413.51

Formula

C26H27N3O2
SMILES

O=C(C[C@@H](C)NC(C1=CC=C(C2=CC=NC=C2)C=C1)=O)N[C@@H](CCC3)C4=C3C=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VU6080195 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VU6080195VU 6080195VU-6080195Ser/Thr KinaseProtein Serine-Threonine KinaseTAOK1 kinaseratTAOK family kinasetauopathiesneurodevelopmental disordersTAOK3 kinaseblood-brain barrierTAOK2 kinaseInhibitorinhibitorinhibit

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