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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
TFP
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "TFP" in MCE Product Catalog:
10
Research Areas:
Trifluoperazine, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine is a potent α1-adrenergic receptor antagonist. Trifluoperazine is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine can be used for the research of schizophrenia. Trifluoperazine acts as a reversible inhibitor of influenza virus morphogenesis .
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Trifluoperazine dihydrochloride, an antipsychotic agent, acts by blocking central dopamine receptors. Trifluoperazine dihydrochloride is a potent α1-adrenergic receptor antagonist. Trifluoperazine dihydrochloride is a potent NUPR1 inhibitor exerting anticancer activity. Trifluoperazine dihydrochloride is a calmodulin inhibitor, and also inhibits P-glycoprotein. Trifluoperazine dihydrochloride can be used for the research of schizophrenia. Trifluoperazine dihydrochloride acts as a reversible inhibitor of influenza virus morphogenesis .
Synonyms: (±)-H3L28
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(±)-H3RESCA-TFP ((±)-H3L28) is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA). (±)-H3RESCA-TFP can be used to conjugate the chelator with a biomolecule via amine coupling (e.g., N terminus and/or the ε-amino groups of lysine) .
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Bis-Mal-Lysine-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-W190728
CAS No.: 1446282-42-3
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Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-W096112
CAS No.: 1446282-34-3
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TFP-PEG3-TFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Biotin-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-138437
CAS No.: 1818294-49-3
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Azido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-TFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-W800839
CAS No.: 2268817-73-6
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TCO-PEG4-TFP Ester is an amine-reactive labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers. A 2,3,5,6-tetrafluorophenol (TFP) is a reactive ester that displays much better stability toward hydrolysis in aqueous media resulting in more efficiency and better reproducible labeling of biopolymers. TFP ester of carboxylic acids react with primary amines at the same rate as NHS ester forming covalent amide bond that is identical to one formed by the reaction between primary amines and NHS esters or sulfo-NHS esters.
Cat. No.: HY-404548
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Sulfo-TAG TFP ester disodium is a tetrafluorophenyl (TFP) ester that conjugates with proteins via primary amine groups. Sulfo-TAG TFP ester disodium exhibits stronger hydrophobicity than NHS esters and higher resistance to hydrolysis in aqueous solutions. Sulfo-TAG TFP ester disodium can be used for antibody labeling.
Cat. No.: HY-141173
CAS No.: 2353410-06-5
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TCO-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Mal-amido-PEG2-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Mal-amido-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Cat. No.: HY-151789
CAS No.: 2268816-76-6
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Sulfo DBCO-TFP Ester is a water-soluble, sulfo-containing click chemistry reagent. Sulfo DBCO-TFP Ester enables simple and efficient incorporation of sulfo-DBCO moieties onto amine-containing molecules .
Cat. No.: HY-D1113
CAS No.: 878546-79-3
Cat. No.: HY-173569
CAS No.: 2764923-68-2
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DBCO-propargyl-PEG5-TFP ester is an amine-reactive labeling reagent. DBCO-propargyl-PEG5-TFP ester contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition (SPAAC) reaction with molecules containing an azide group [1] .
Cat. No.: HY-W144703
CAS No.: 3241-20-1
Synonyms: 9-Aminoheptadecane
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Heptadecan-9-amine (9-Aminoheptadecane) is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.
Cat. No.: HY-140724
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Bis-PEG5000-TFP ester is a PEG derivative containing an acrylate functional group for drug delivery .
Cat. No.: HY-140904
CAS No.: 3017961-69-9
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Biotin-PEG12-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
