3 Results for "

TRAP-6-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "TRAP-6-IN-1" in MCE Product Catalog:

Cat. No.: HY-146333
CAS No.: 2068737-10-8
TRAP-6-IN-1 (Compound 8) is a dual collagen and TRAP-6 inhibitor with IC50 values of 17.12 µM and 11.88 µM against collagen and TRAP-6, respectively. TRAP-6-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-P0078
CAS No.: 141136-83-6
Synonyms: PAR-1 agonist peptide; ThrombIN Receptor Activator Peptide 6
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4 .
loading...
    loading...
Cat. No.: HY-136501
CAS No.: 491611-55-3
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

MRS2395, an dipivaloyl derivative, is a potent P2Y12 receptor antagonist. MRS2395 inhibits ADP-induced platelet activation with a Ki of 3.6 μM. MRS2395 inhibits cAMP induced by ADP in rat platelets in the presence of PGE1 with an IC50 of 7 µM. MRS2395 enhances platelet dense granule release in response to TRAP-6 .
loading...
    loading...